What Is Down Syndrome - St. Louis Children's Hospital

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What Is Down Syndrome

Down syndrome is one of the most common genetic conditions, affecting approximately one in every 800-1,000 children.
It is caused by the presence of an extra copy of chromosome 21 and is also referred to as trisomy 21. The additional genetic material alters the course of development and results in certain kinds of birth defects, as well as developmental delays in motor skills, language and other areas of learning.
Most of the birth defects can be corrected with surgery. There is a broad range of mental abilities, behavior and physical development in Down syndrome.
Individuals with Down syndrome benefit greatly from early developmental intervention, special education and a specific plan of medical care.

St. Louis Children's Hospital is affiliated with Washington University School of Medicine.

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