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Joshua B Rubin, MD, PhD

Dr. Rubin cares for children with cancer and blood diseases. He has a special interest in neuro-oncology.
Div Of Hematology/Oncology
54
Male
2003
2000
Hematology-Pediatric - certified
Oncology-Pediatric - certified
Pediatrics - certified
Siteman Cancer Center
St. Louis Children's Hospital

For Patients:
To request an appointment, call 800.678.KIDS (5437) or fill out our online form.

For Referring Physicians:
To refer a patient, call Children's Direct at 800.678.HELP (4357).

For Patients:
To request an appointment, call 800.678.KIDS (5437) or fill out our online form.

For Referring Physicians:
To refer a patient, call Children's Direct at 800.678.HELP (4357).

 

  Public transportation available |   Handicap accessible
One Children's Place
Suite 9S
Saint Louis, MO 63110
314.454.6018
  
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Education

Medical School: Albert Einstein College of Medicine New York
Internship: Boston Children's Hospital Boston Massachusetts
Residency: Boston Children's Hospital Boston Massachusetts
Fellowship: Dana Farber Cancer Institute

Health Plans Accepted

Aetna Choice POS I & II
Aetna HMO
Aetna Medicare Open Access HMO/POS
Aetna Medicare Plan HMO
Aetna Medicare Plan PPO
Aetna Open Access Managed Choice
Aetna Open Choice PPO
Anthem BCBS Blue Access
Anthem BCBS Blue Access Choice
Anthem Blue Preferred HMO (BOONE)
BCBS of IL HMO
BCBS of IL PPO
Beech Street/Capp Care PPO
Best Doctors Inc
Cigna Open Access HMO/POS
Cigna PPO
Community Health Network PPO
Coventry Advantra HMO/POS-MCARE
Coventry Gold Advantage - MCARE
Coventry Healthcare ASO
Coventry Healthcare HMO
Coventry/Coventry One PPO
Essence Medicare Advantage & Plus
First Health Coventry
Great-West HMO/POS
Great-West Open Access
Great-West PPO
Health Alliance HMO & PPO
HealthCare USA MC+
Healthlink Open Access/HMO/POS
Healthlink PPO
HFN Inc. PPO
Home State-MC+
Humana Choice Care PPO
Humana Choice/Regional PPO - MCARE
Humana Gold Choice PFFS - MCARE
Humana Gold Plus HMO - MCARE
Humana POS - MCARE
Medicaid MO/ Missouri HealthNet
Medicare
Mercy Health Plan HMO/POS
Mercy Health Plan PPO
MO Medicaid Secondary to Medicare
MultiPlan PPO
Primrose Tertiary/Quarternary
Private Health Care Systems PPO
Tricare/Triwest Prime HMO/POS
Tricare/Triwest Standard/ Extra PPO
UHC/AARP MCARE Complete Choice PPO
UHC/AARP MCARE Complete HMO
UHC/AARP MCARE CompleteEssen. HMO
UHC/AARP MCARE Dual Complete
Union Pacific RR Emp. Health System
United Healthcare Choice/Choice+
United Healthcare PPO/ Options
United Healthcare Select/Select+POS
USA Managed Care Org
Verify insurance with office
Worker's Compensation

Suppression of G protein-coupled Receptor Kinase 3 expression is a feature of Classical GBM that is required for maximal growth.Woerner BM, Luo J, Brown KR, Jackson E, Dahiya SM, Mischel PS, Benovic J, Piwnica-Worms D, Rubin JB.Mol Cancer Res. 2011 Nov 15. [Epub ahead of print]

PMID:
22086906
[PubMed - as supplied by publisher]

Related citationsCXCR4 activation defines a new subgroup of Sonic Hedgehog driven Medulloblastoma.Sengupta R, Dubuc A, Ward S, Yang L, Northcott P, Woerner BM, Kroll K, Luo J, Taylor MD, Wechsler-Reya RJ, Rubin JB.Cancer Res. 2011 Nov 3. [Epub ahead of print]

PMID:
22052462
[PubMed - as supplied by publisher]

Related citationsOligodendrogliomas in children.Creach KM, Rubin JB, Leonard JR, Limbrick DD, Smyth MD, Dacey R, Rich KM, Dowling JL, Grubb RL Jr, Linette GP, King AA, Michalski JM, Park TS, Perry A, Simpson JR, Mansur DB.J Neurooncol. 2012 Jan;106(2):377-82. Epub 2011 Aug 13.

PMID:
21842314
[PubMed - in process]

Related citationsTreating brain tumors with PDE4 inhibitors.Sengupta R, Sun T, Warrington NM, Rubin JB.Trends Pharmacol Sci. 2011 Jun;32(6):337-44. Epub 2011 Mar 28.

PMID:
21450351
[PubMed - indexed for MEDLINE]

Related citationsGlioblastoma in children: a single-institution experience.Perkins SM, Rubin JB, Leonard JR, Smyth MD, El Naqa I, Michalski JM, Simpson JR, Limbrick DL, Park TS, Mansur DB.Int J Radiat Oncol Biol Phys. 2011 Jul 15;80(4):1117-21. Epub 2011 Jan 8.

PMID:
21220190
[PubMed - indexed for MEDLINE]

Related citationsPostoperative imaging surveillance in pediatric pilocytic astrocytomas.Dorward IG, Luo J, Perry A, Gutmann DH, Mansur DB, Rubin JB, Leonard JR.J Neurosurg Pediatr. 2010 Oct;6(4):346-52.

PMID:
20887107
[PubMed - indexed for MEDLINE]

Related citationsHighlights from the latest articles in glioma immunotherapy.Goldhoff P, Rubin JB.Immunotherapy. 2010 Jan;2(1):9-12. No abstract available.

PMID:
20635886
[PubMed]

Free ArticleRelated citationsCXCL12 alone is insufficient for gliomagenesis in Nf1 mutant mice.Sun T, Gianino SM, Jackson E, Piwnica-Worms D, Gutmann DH, Rubin JB.J Neuroimmunol. 2010 Jul 27;224(1-2):108-13.

PMID:
20554030
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsCyclic AMP suppression is sufficient to induce gliomagenesis in a mouse model of neurofibromatosis-1.Warrington NM, Gianino SM, Jackson E, Goldhoff P, Garbow JR, Piwnica-Worms D, Gutmann DH, Rubin JB.Cancer Res. 2010 Jul 15;70(14):5717-27. Epub 2010 Jun 15.

PMID:
20551058
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsRadiation therapy for pilocytic astrocytomas of childhood.Mansur DB, Rubin JB, Kidd EA, King AA, Hollander AS, Smyth MD, Limbrick DD, Park TS, Leonard JR.Int J Radiat Oncol Biol Phys. 2011 Mar 1;79(3):829-34. Epub 2010 Apr 24.

PMID:
20421157
[PubMed - indexed for MEDLINE]

Related citationsBrainstem glioma presenting as pruritus in children with neurofibromatosis-1.Darken RS, Bogitch R, Leonard J, Perry A, McKinstry RC, Gutmann DH, Rubin JB.J Pediatr Hematol Oncol. 2009 Dec;31(12):972-6.

PMID:
19935099
[PubMed - indexed for MEDLINE]

Related citationsMorphine increases brain levels of ferritin heavy chain leading to inhibition of CXCR4-mediated survival signaling in neurons.Sengupta R, Burbassi S, Shimizu S, Cappello S, Vallee RB, Rubin JB, Meucci O.J Neurosci. 2009 Feb 25;29(8):2534-44.

PMID:
19244528
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsOnly in congenial soil: the microenvironment in brain tumorigenesis.Rubin JB.Brain Pathol. 2009 Jan;19(1):144-9. Review.

PMID:
19076779
[PubMed - indexed for MEDLINE]

Related citationsTargeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression.Goldhoff P, Warrington NM, Limbrick DD Jr, Hope A, Woerner BM, Jackson E, Perry A, Piwnica-Worms D, Rubin JB.Clin Cancer Res. 2008 Dec 1;14(23):7717-25.

PMID:
19047098
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsChemokine signaling in cancer: one hump or two?Rubin JB.Semin Cancer Biol. 2009 Apr;19(2):116-22. Epub 2008 Oct 17. Review.

PMID:
18992347
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsFeasibility of small animal cranial irradiation with the microRT system.Kiehl EL, Stojadinovic S, Malinowski KT, Limbrick D, Jost SC, Garbow JR, Rubin JB, Deasy JO, Khullar D, Izaguirre EW, Parikh PJ, Low DA, Hope AJ.Med Phys. 2008 Oct;35(10):4735-43.

PMID:
18975718
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsTargeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML.Zeng Z, Shi YX, Samudio IJ, Wang RY, Ling X, Frolova O, Levis M, Rubin JB, Negrin RR, Estey EH, Konoplev S, Andreeff M, Konopleva M.Blood. 2009 Jun 11;113(24):6215-24. Epub 2008 Oct 27.

PMID:
18955566
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsUse of thalidomide to diminish growth velocity in a life-threatening congenital intracranial hemangioma.Frei-Jones M, McKinstry RC, Perry A, Leonard JR, Park TS, Rubin JB.J Neurosurg Pediatr. 2008 Aug;2(2):125-9.

PMID:
18671617
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsRethinking brain tumors: the fourth Mouse Models of Human Cancers Consortium nervous system tumors workshop.Reilly KM, Rubin JB, Gilbertson RJ, Garbow JR, Roussel MF, Gutmann DH.Cancer Res. 2008 Jul 15;68(14):5508-11. No abstract available.

PMID:
18632599
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsPreclinical cancer therapy in a mouse model of neurofibromatosis-1 optic glioma.Hegedus B, Banerjee D, Yeh TH, Rothermich S, Perry A, Rubin JB, Garbow JR, Gutmann DH.Cancer Res. 2008 Mar 1;68(5):1520-8.

PMID:
18316617
[PubMed - indexed for MEDLINE]

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