Print This Page
Paul W Hruz, MD

Paul W Hruz, MD

Dr. Hruz specializes in Pediatric Endocrinology and diabetes.
Div Of Pediatric Endo/Metab
48
Male
1997
1997
Endocrinology-Pediatric - certified
Pediatrics - certified
Barnes-Jewish Hospital
St. Louis Children's Hospital

For Patients:
To request an appointment, call 800.678.KIDS (5437) or fill out our online form.

For Referring Physicians:
To refer a patient, call Children's Direct at 800.678.HELP (4357).

For Patients:
To request an appointment, call 800.678.KIDS (5437) or fill out our online form.

For Referring Physicians:
To refer a patient, call Children's Direct at 800.678.HELP (4357).

 

  Public transportation available |   Handicap accessible
1 Children's Place
2Nd Floor Suite D
St. Louis, MO 63110
314.454.6051
  
Javascript is required to view this map.

Education

Medical School: Medical College of Wisconsin Milwaukee
Internship: University of Washington Seattle
Residency: University of Washington Seattle
Fellowship: Washington University School of Medicine St. Louis Missouri

Health Plans Accepted

Aetna Medicare HMO
Aetna Medicare Open Access (HMO/POS
Aetna PPO
Anthem BCBS Blue Access Choice PPO
Anthem BCBS Blue Access PPO
BCBS of IL HMO
BCBS of IL PPO
Beech Street/Capp Care PPO
Best Doctors Inc
Cigna Open Access HMO/POS
Cigna PPO
Community Care Network PPO
Coventry Advantra HMO/POS-Medicare
Coventry ASO
Coventry Gold Advantage - Medicare
Coventry HMO/POS
Coventry/Coventry One PPO
Essence Advantage & Advantage Plus
First Health
Great-West HMO/POS
Great-West Open Access
Great-West PPO
Health Alliance HMO & PPO
HealthCare USA MC+
Healthlink Open Access/HMO/POS
Healthlink PPO
HFN Inc. PPO
Home State-MC+
Humana Choice PPO - Medicare
Humana Gold Choice PFFS - Medicare
Humana Gold Plus HMO - Medicare
Humana POS-Medicare
Humana PPO/ChoiceCare Network
Illinois Public Aid/Health Connect
Medicaid MO/ Missouri HealthNet
Medicare
Mercy Health Plan HMO/POS
Mercy Health Plan PPO
MO Medicaid Secondary to Medicare
MultiPlan PPO
Primrose Tertiary/Quarternary
Private Health Care Systems PPO
Tricare/Triwest Prime HMO/POS
Tricare/Triwest Standard/ Extra PPO
UHC/AARP MCARE Complete Choice PPO
UHC/AARP MCARE Complete HMO
UHC/AARP MCARE CompleteEssen. HMO
UHC/AARP MCARE Dual Complete
Union Pacific RR Emp. Health System
United Healthcare Choice/Choice+
United Healthcare PPO/ Options
United Healthcare Select/Select+POS
USA Managed Care Org
Verify insurance with office
Worker's Compensation

HIV protease inhibitors act as competitive inhibitors of the cytoplasmic glucose binding site of GLUTs with differing affinities for GLUT1 and GLUT4.Hresko RC, Hruz PW.PLoS One. 2011;6(9):e25237. Epub 2011 Sep 23.

PMID:
21966466
[PubMed - in process]

Free PMC ArticleRelated citationsAcute sulfonylurea therapy at disease onset can cause permanent remission of KATP-induced diabetes.Remedi MS, Agapova SE, Vyas AK, Hruz PW, Nichols CG.Diabetes. 2011 Oct;60(10):2515-22. Epub 2011 Aug 3.

PMID:
21813803
[PubMed - indexed for MEDLINE]

Related citationsMolecular mechanisms for insulin resistance in treated HIV-infection.Hruz PW.Best Pract Res Clin Endocrinol Metab. 2011 Jun;25(3):459-68. doi: 10.1016/j.beem.2010.10.017. Review.

PMID:
21663839
[PubMed - indexed for MEDLINE]

Related citationsExenatide improves glucose homeostasis and prolongs survival in a murine model of dilated cardiomyopathy.Vyas AK, Yang KC, Woo D, Tzekov A, Kovacs A, Jay PY, Hruz PW.PLoS One. 2011 Feb 17;6(2):e17178.

PMID:
21359201
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsGS-8374, a novel HIV protease inhibitor, does not alter glucose homeostasis in cultured adipocytes or in a healthy-rodent model system.Hruz PW, Yan Q, Tsai L, Koster J, Xu L, Cihlar T, Callebaut C.Antimicrob Agents Chemother. 2011 Apr;55(4):1377-82. Epub 2011 Jan 18.

PMID:
21245443
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsLiver regeneration is impaired in lipodystrophic fatty liver dystrophy mice.Gazit V, Weymann A, Hartman E, Finck BN, Hruz PW, Tzekov A, Rudnick DA.Hepatology. 2010 Dec;52(6):2109-17. doi: 10.1002/hep.23920. Epub 2010 Oct 21.

PMID:
20967828
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsEffects of the HIV protease inhibitor ritonavir on GLUT4 knock-out mice.Vyas AK, Koster JC, Tzekov A, Hruz PW.J Biol Chem. 2010 Nov 19;285(47):36395-400. Epub 2010 Sep 23.

PMID:
20864532
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsAcipimox, an inhibitor of lipolysis, attenuates atherogenesis in LDLR-null mice treated with HIV protease inhibitor ritonavir.Guo W, Wong S, Pudney J, Jasuja R, Hua N, Jiang L, Miller A, Hruz PW, Hamilton JA, Bhasin S.Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2028-32. Epub 2009 Sep 17.

PMID:
19762785
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsGenetic disruption of myostatin reduces the development of proatherogenic dyslipidemia and atherogenic lesions in Ldlr null mice.Tu P, Bhasin S, Hruz PW, Herbst KL, Castellani LW, Hua N, Hamilton JA, Guo W.Diabetes. 2009 Aug;58(8):1739-48. Epub 2009 Jun 9.

PMID:
19509018
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsHIV protease inhibitors and insulin resistance: lessons from in-vitro, rodent and healthy human volunteer models.Hruz PW.Curr Opin HIV AIDS. 2008 Nov;3(6):660-5.

PMID:
19373039
[PubMed]

Free PMC ArticleRelated citationsThe role of protease inhibitors in the pathogenesis of HIV-associated lipodystrophy: cellular mechanisms and clinical implications.Flint OP, Noor MA, Hruz PW, Hylemon PB, Yarasheski K, Kotler DP, Parker RA, Bellamine A.Toxicol Pathol. 2009;37(1):65-77. Epub 2009 Jan 26. Review.

PMID:
19171928
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsHIV protease inhibitors that block GLUT4 precipitate acute, decompensated heart failure in a mouse model of dilated cardiomyopathy.Hruz PW, Yan Q, Struthers H, Jay PY.FASEB J. 2008 Jul;22(7):2161-7. Epub 2008 Feb 6.

PMID:
18256305
[PubMed - indexed for MEDLINE]

Free ArticleRelated citationsMolecular Mechanisms for Altered Glucose Homeostasis in HIV Infection.Hruz PW.Am J Infect Dis. 2006;2(3):187-192.

PMID:
17186064
[PubMed]

Free PMC ArticleRelated citationsTipranavir without ritonavir does not acutely induce peripheral insulin resistance in a rodent model.Hruz PW, Yan Q.J Acquir Immune Defic Syndr. 2006 Dec 15;43(5):624-5. No abstract available.

PMID:
17133213
[PubMed - indexed for MEDLINE]

Related citationsRosiglitazone inhibits mouse liver regeneration.Turmelle YP, Shikapwashya O, Tu S, Hruz PW, Yan Q, Rudnick DA.FASEB J. 2006 Dec;20(14):2609-11. Epub 2006 Oct 31.

PMID:
17077279
[PubMed - indexed for MEDLINE]

Free ArticleRelated citationsDirect comparison of the acute in vivo effects of HIV protease inhibitors on peripheral glucose disposal.Yan Q, Hruz PW.J Acquir Immune Defic Syndr. 2005 Dec 1;40(4):398-403.

PMID:
16280693
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsDisruption of hepatic adipogenesis is associated with impaired liver regeneration in mice.Shteyer E, Liao Y, Muglia LJ, Hruz PW, Rudnick DA.Hepatology. 2004 Dec;40(6):1322-32.

PMID:
15565660
[PubMed - indexed for MEDLINE]

Related citationsA structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity.Hertel J, Struthers H, Horj CB, Hruz PW.J Biol Chem. 2004 Dec 31;279(53):55147-52. Epub 2004 Oct 20.

PMID:
15496402
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsDelayed hepatocellular mitotic progression and impaired liver regeneration in early growth response-1-deficient mice.Liao Y, Shikapwashya ON, Shteyer E, Dieckgraefe BK, Hruz PW, Rudnick DA.J Biol Chem. 2004 Oct 8;279(41):43107-16. Epub 2004 Jul 20.

PMID:
15265859
[PubMed - indexed for MEDLINE]

Free ArticleRelated citationsHIV protease inhibitors acutely impair glucose-stimulated insulin release.Koster JC, Remedi MS, Qiu H, Nichols CG, Hruz PW.Diabetes. 2003 Jul;52(7):1695-700.

PMID:
12829635
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsView More Publications