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Gynecology, Pediatric and Adolescent

David G Mutch, MD

David G Mutch, MD

Dr. David Mutch focuses his practice on gynecological cancers; which include endometrial cancer, vulva cancer, cervical cancer and ovarian cancer. He is the Ira C. and Judith Gall Professor of Obstetrics and Gynecology, Vice Chairman of Gynecology and Director of the Division of Gynecologic Oncology at Washington University School of Medicine. Dr. Mutch is consistently recognized in "The Best Doctors in America" list.
Division Of Gyn Oncology
Gynecologic Oncology - certified
Gynecology - certified
Obstetrics - certified
Progress West Hospital
Siteman Cancer Center
Christian Hospital
Missouri Baptist Medical Center
St. Louis Children's Hospital
Barnes-Jewish West County Hospital
Barnes-Jewish Hospital

For Patients:
To request an appointment, call 800.678.KIDS (5437) or fill out our online form.

For Referring Physicians:
To refer a patient, call Children's Direct at 800.678.HELP (4357).

For Patients:
To request an appointment, call 800.678.KIDS (5437) or fill out our online form.

For Referring Physicians:
To refer a patient, call Children's Direct at 800.678.HELP (4357).


  Public transportation available |   Handicap accessible
3023 North New Ballas Road
Building D Suite 450
St. Louis, MO 63131
Center For Advanced Medicine
4921 Parkview Place Suite 13C
St. Louis, MO 63110
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Medical School: Washington University School of Medicine St. Louis Missouri
Internship: Washington University School of Medicine St. Louis Missouri
Residency: Washington University School of Medicine St. Louis Missouri
Fellowship: Duke University Durham North Carolina

Health Plans Accepted

Aetna Medicare HMO
Aetna Medicare Open Access (HMO/POS
Aetna PPO
Anthem BCBS Blue Access Choice PPO
Anthem BCBS Blue Access PPO
Beech Street/Capp Care PPO
Best Doctors Inc
Cigna Open Access HMO/POS
Cigna PPO
Community Health Network PPO
Coventry Advantra HMO/POS-Medicare
Coventry ASO
Coventry Gold Advantage - Medicare
Coventry HMO/POS
Coventry/Coventry One PPO
Essence Advantage & Advantage Plus
First Health
Great-West HMO/POS
Great-West Open Access
Great-West PPO
Health Alliance HMO & PPO
Healthlink Open Access/HMO/POS
Healthlink PPO
Humana Choice PPO - Medicare
Humana Gold Choice PFFS - Medicare
Humana Gold Plus HMO - Medicare
Humana POS-Medicare
Humana PPO/ChoiceCare Network
Illinois Public Aid/Health Connect
Mercy Health Plan HMO/POS
Mercy Health Plan PPO
MO Medicaid Secondary to Medicare
MultiPlan PPO
Primrose Tertiary/Quarternary
Private Health Care Systems PPO
Tricare/Triwest Prime HMO/POS
Tricare/Triwest Standard/ Extra PPO
UHC/AARP MCARE Complete Choice PPO
UHC/AARP MCARE Dual Complete
Union Pacific RR Emp. Health System
United Healthcare Choice/Choice+
United Healthcare PPO/ Options
United Healthcare Select/Select+POS
USA Managed Care Org
Verify insurance with office
Worker's Compensation

High Frequency Strand Slippage Mutations in CTCF in MSI-Positive Endometrial Cancers.

Zighelboim I, Mutch DG, Knapp A, Ding L, Xie M, Cohn DE, Goodfellow PJ.

Hum Mutat. 2013 Oct 15. doi: 10.1002/humu.22463. [Epub ahead of print]

[PubMed - as supplied by publisher]

Disclosing a diagnosis of cancer: considerations specific to gynecologic oncology patients.

Kuroki LM, Zhao Q, Jeffe DB, Powell MA, Hagemann AR, Thaker PH, Massad LS, Mutch DG, Zighelboim I.

Obstet Gynecol. 2013 Nov;122(5):1033-9. doi: 10.1097/AOG.0b013e3182a9bf42.

[PubMed - in process]

Phase II study of bevacizumab and pemetrexed for recurrent or persistent epithelial ovarian, fallopian tube or primary peritoneal cancer.

Hagemann AR, Novetsky AP, Zighelboim I, Gao F, Massad LS, Thaker PH, Powell MA, Mutch DG, Wright JD.

Gynecol Oncol. 2013 Dec;131(3):535-40. doi: 10.1016/j.ygyno.2013.09.032. Epub 2013 Oct 4.

[PubMed - in process]

Promoter Hypomethylation of EpCAM-Regulated Bone Morphogenetic Protein Gene Family in Recurrent Endometrial Cancer.

Hsu YT, Gu F, Huang YW, Liu J, Ruan J, Huang RL, Wang CM, Chen CL, Jadhav RR, Lai HC, Mutch DG, Goodfellow PJ, Thompson IM, Kirma NB, Huang TH.

Clin Cancer Res. 2013 Nov 15;19(22):6272-85. doi: 10.1158/1078-0432.CCR-13-1734. Epub 2013 Sep 27.

[PubMed - in process]

Timing of referral for genetic counseling and genetic testing in patients with ovarian, fallopian tube, or primary peritoneal carcinoma.

Novetsky AP, Smith K, Babb SA, Jeffe DB, Hagemann AR, Thaker PH, Powell MA, Mutch DG, Massad LS, Zighelboim I.

Int J Gynecol Cancer. 2013 Jul;23(6):1016-21. doi: 10.1097/IGC.0b013e3182994365.

[PubMed - in process]

Multicenter phase II trial of topotecan, cisplatin and bevacizumab for recurrent or persistent cervical cancer.

Zighelboim I, Wright JD, Gao F, Case AS, Massad LS, Mutch DG, Powell MA, Thaker PH, Eisenhauer EL, Cohn DE, Valea FA, Alvarez Secord A, Lippmann LT, Dehdashti F, Rader JS.

Gynecol Oncol. 2013 Jul;130(1):64-8. doi: 10.1016/j.ygyno.2013.04.009. Epub 2013 Apr 13.

[PubMed - indexed for MEDLINE]

In vitro chemoresponse to cisplatin and outcomes in cervical cancer.

Grigsby PW, Zighelboim I, Powell MA, Mutch DG, Schwarz JK.

Gynecol Oncol. 2013 Jul;130(1):188-91. doi: 10.1016/j.ygyno.2013.04.005. Epub 2013 Apr 10.

[PubMed - indexed for MEDLINE]

Disparities in ovarian cancer care quality and survival according to race and socioeconomic status.

Bristow RE, Powell MA, Al-Hammadi N, Chen L, Miller JP, Roland PY, Mutch DG, Cliby WA.

J Natl Cancer Inst. 2013 Jun 5;105(11):823-32. doi: 10.1093/jnci/djt065. Epub 2013 Mar 28.

[PubMed - indexed for MEDLINE]

Intestinal perforation in gynecologic oncology: do all patients benefit from surgical management?

Garg G, Massad LS, Pourabolghasem S, Zhou G, Powell MA, Thaker PH, Hagemann AR, Wilkinson-Ryan I, Mutch DG.

Gynecol Oncol. 2013 Jun;129(3):538-43. doi: 10.1016/j.ygyno.2013.03.004. Epub 2013 Mar 13.

[PubMed - indexed for MEDLINE]

Targeted endometrial cancer therapy as a future prospect.

Thanapprapasr D, Cheewakriangkrai C, Likittanasombut P, Thanapprapasr K, Mutch DG.

Womens Health (Lond Engl). 2013 Mar;9(2):189-99. doi: 10.2217/whe.13.4.

[PubMed - indexed for MEDLINE]

Low yield of residual vulvar carcinoma and dysplasia upon re-excision for close or positive margins.

Ioffe YJ, Erickson BK, Foster KE, Mutch DG, Powell MA, Thaker PH, Hagemann AR, Conner MG, Huh WK, Massad LS.

Gynecol Oncol. 2013 Jun;129(3):528-32. doi: 10.1016/j.ygyno.2013.02.033. Epub 2013 Mar 6.

[PubMed - indexed for MEDLINE]

Wilms' tumor 1 protein and estrogen receptor beta expression are associated with poor outcomes in uterine carcinosarcoma.

Guntupalli SR, Cao D, Shroff R, Gao F, Menias C, Stewart Massad L, Powell MA, Mutch DG, Thaker PH.

Ann Surg Oncol. 2013 Jul;20(7):2373-9. doi: 10.1245/s10434-012-2838-9. Epub 2013 Jan 24.

[PubMed - in process]

Lithium chloride and inhibition of glycogen synthase kinase 3β as a potential therapy for serous ovarian cancer.

Novetsky AP, Thompson DM, Zighelboim I, Thaker PH, Powell MA, Mutch DG, Goodfellow PJ.

Int J Gynecol Cancer. 2013 Feb;23(2):361-6. doi: 10.1097/IGC.0b013e31827cfecb.

[PubMed - indexed for MEDLINE]

The utility and management of vaginal cytology after treatment for endometrial cancer.

Novetsky AP, Kuroki LM, Massad LS, Hagemann AR, Thaker PH, Powell MA, Mutch DG, Zighelboim I.

Obstet Gynecol. 2013 Jan;121(1):129-35.

[PubMed - indexed for MEDLINE]

The risk of lymph node metastasis with positive peritoneal cytology in endometrial cancer.

Garg G, Gao F, Wright JD, Hagemann AR, Zighelboim I, Mutch DG, Powell MA.

Int J Gynecol Cancer. 2013 Jan;23(1):90-7. doi: 10.1097/IGC.0b013e318275afd2.

[PubMed - indexed for MEDLINE]

Frequent mutations in the RPL22 gene and its clinical and functional implications.

Novetsky AP, Zighelboim I, Thompson DM Jr, Powell MA, Mutch DG, Goodfellow PJ.

Gynecol Oncol. 2013 Mar;128(3):470-4. doi: 10.1016/j.ygyno.2012.10.026. Epub 2012 Nov 2.

[PubMed - indexed for MEDLINE]
Free PMC Article

Elevated white blood cell count at the time of recurrence diagnosis is an indicator of short survival in patients with recurrent cervical cancer.

Mabuchi S, Matsumoto Y, Hamasaki T, Kawano M, Hisamatsu T, Mutch DG, Kimura T.

Int J Gynecol Cancer. 2012 Nov;22(9):1545-51. doi: 10.1097/IGC.0b013e31826ea0eb.

[PubMed - indexed for MEDLINE]

Positive peritoneal cytology is an independent risk-factor in early stage endometrial cancer.

Garg G, Gao F, Wright JD, Hagemann AR, Mutch DG, Powell MA.

Gynecol Oncol. 2013 Jan;128(1):77-82. doi: 10.1016/j.ygyno.2012.09.026. Epub 2012 Sep 29.

[PubMed - indexed for MEDLINE]

Use of mutation profiles to refine the classification of endometrial carcinomas.

McConechy MK, Ding J, Cheang MC, Wiegand KC, Senz J, Tone AA, Yang W, Prentice LM, Tse K, Zeng T, McDonald H, Schmidt AP, Mutch DG, McAlpine JN, Hirst M, Shah SP, Lee CH, Goodfellow PJ, Gilks CB, Huntsman DG.

J Pathol. 2012 Sep;228(1):20-30. doi: 10.1002/path.4056. Epub 2012 Jul 18.

[PubMed - indexed for MEDLINE]

FGFR2 point mutations in 466 endometrioid endometrial tumors: relationship with MSI, KRAS, PIK3CA, CTNNB1 mutations and clinicopathological features.

Byron SA, Gartside M, Powell MA, Wellens CL, Gao F, Mutch DG, Goodfellow PJ, Pollock PM.

PLoS One. 2012;7(2):e30801. doi: 10.1371/journal.pone.0030801. Epub 2012 Feb 23.

[PubMed - indexed for MEDLINE]
Free PMC Article

Gynecology, Pediatric and Adolescent