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Patrick Y Jay, MD, PhD

Patrick Y Jay, MD, PhD

Dr. Jay is a pediatric cardiologist. He sees children referred for evaluation or for continuing care of heart disease. Dr. Jay is happy to provide a second opinion on any heart disease diagnosis or heart disease treatment recommendation your child has been given.
Div Of Pediatric Cardiology
48
Male
2004
2001
Cardiology-Pediatric - certified
Pediatrics
St. Louis Children's Hospital

For Patients:
To request an appointment, call 800.678.KIDS (5437) or fill out our online form.

For Referring Physicians:
To refer a patient, call Children's Direct at 800.678.HELP (4357).

For Patients:
To request an appointment, call 800.678.KIDS (5437) or fill out our online form.

For Referring Physicians:
To refer a patient, call Children's Direct at 800.678.HELP (4357).

 

  Public transportation available |   Handicap accessible
One Children's Place
2Nd Floor Suite D
Saint Louis, MO 63110
314.454.6095
  
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Education

Medical School: Washington University School of Medicine St. Louis Missouri
Residency: Children's Hospital Boston Massachusetts
Fellowship: Children's Hospital Boston Massachusetts

Health Plans Accepted

Aetna HMO/Open Access
Aetna Managed Choice POS
Aetna Medicare HMO
Aetna Medicare Open Access (HMO/POS
Aetna Medicare PPO
Aetna POS/PPO/Choice
Aetna PPO
Anthem BCBS Blue Access Choice PPO
Anthem BCBS Blue Access PPO
Anthem BCBS Blue Preferred HMO/POS
BCBS of IL HMO
BCBS of IL PPO
Beech Street/Capp Care PPO
Best Doctors Inc
Cigna Open Access HMO/POS
Cigna PPO
Community Care Network PPO
Coventry Advantra HMO/POS-Medicare
Coventry ASO
Coventry Gold Advantage - Medicare
Coventry HMO/POS
Coventry/Coventry One PPO
Essence Advantage & Advantage Plus
First Health
Great-West HMO/POS
Great-West Open Access
Great-West PPO
Health Alliance HMO & PPO
HealthCare USA MC+
Healthlink Open Access/HMO/POS
Healthlink PPO
HFN Inc. PPO
Home State-MC+
Humana Choice PPO - Medicare
Humana Gold Choice PFFS - Medicare
Humana Gold Plus HMO - Medicare
Humana POS-Medicare
Humana PPO/ChoiceCare Network
Medicaid MO/ Missouri HealthNet
Medicare
Mercy Health Plan HMO/POS
Mercy Health Plan PPO
MO Medicaid Secondary to Medicare
MultiPlan PPO
Primrose Tertiary/Quarternary
Private Health Care Systems PPO
Tricare/Triwest Prime HMO/POS
Tricare/Triwest Standard/ Extra PPO
UHC/AARP MCARE Complete Choice PPO
UHC/AARP MCARE Complete HMO
UHC/AARP MCARE CompleteEssen. HMO
UHC/AARP MCARE Dual Complete
Union Pacific RR Emp. Health System
United Healthcare Choice/Choice+
United Healthcare PPO/ Options
United Healthcare Select/Select+POS
USA Managed Care Org
Verify insurance with office
Worker's Compensation

Enhanced cardiac PI3Kα signalling mitigates arrhythmogenic electrical remodeling in pathological hypertrophy and heart failure.

Yang KC, Jay PY, McMullen JR, Nerbonne JM.

Cardiovasc Res. 2011 Nov 29. [Epub ahead of print]

PMID:
22038742
[PubMed - as supplied by publisher]

Cardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor γ coactivator 1α/estrogen related receptor axis.

Mitra MS, Schilling JD, Wang X, Jay PY, Huss JM, Su X, Finck BN.

J Mol Cell Cardiol. 2011 Jul;51(1):120-8. Epub 2011 Apr 28.

PMID:
21549711
[PubMed - indexed for MEDLINE]

Exenatide improves glucose homeostasis and prolongs survival in a murine model of dilated cardiomyopathy.

Vyas AK, Yang KC, Woo D, Tzekov A, Kovacs A, Jay PY, Hruz PW.

PLoS One. 2011 Feb 17;6(2):e17178.

PMID:
21359201
[PubMed - indexed for MEDLINE]
Free PMC Article

GATA4 deficiency impairs ovarian function in adult mice.

Kyrönlahti A, Vetter M, Euler R, Bielinska M, Jay PY, Anttonen M, Heikinheimo M, Wilson DB.

Biol Reprod. 2011 May;84(5):1033-44. Epub 2011 Jan 19.

PMID:
21248289
[PubMed - indexed for MEDLINE]
Free Article

Homeostatic regulation of electrical excitability in physiological cardiac hypertrophy.

Yang KC, Foeger NC, Marionneau C, Jay PY, McMullen JR, Nerbonne JM.

J Physiol. 2010 Dec 15;588(Pt 24):5015-32. Epub 2010 Oct 25.

PMID:
20974681
[PubMed - indexed for MEDLINE]
Free PMC Article

Heterogeneity of genetic modifiers ensures normal cardiac development.

Winston JB, Erlich JM, Green CA, Aluko A, Kaiser KA, Takematsu M, Barlow RS, Sureka AO, LaPage MJ, Janss LL, Jay PY.

Circulation. 2010 Mar 23;121(11):1313-21. Epub 2010 Mar 8.

PMID:
20212279
[PubMed - indexed for MEDLINE]
Free PMC Article

Loss of glypican-3 function causes growth factor-dependent defects in cardiac and coronary vascular development.

Ng A, Wong M, Viviano B, Erlich JM, Alba G, Pflederer C, Jay PY, Saunders S.

Dev Biol. 2009 Nov 1;335(1):208-15. Epub 2009 Sep 4.

PMID:
19733558
[PubMed - indexed for MEDLINE]
Free PMC Article

Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies.

Zhang B, Chang J, Fu M, Huang J, Kashyap R, Salavaggione E, Jain S, Kulkarni S, Deardorff MA, Uzielli ML, Dorsett D, Beebe DC, Jay PY, Heuckeroth RO, Krantz I, Milbrandt J.

PLoS One. 2009;4(5):e5232. Epub 2009 May 1. Erratum in: PLoS One. 2009;4(5). doi: 10.1371/annotation/ea5b7eb5-5087-448a-8325-c8efff1f54d9. Shashikant, Kulkarni [corrected to Kulkarni, Shashikant].

PMID:
19412548
[PubMed - indexed for MEDLINE]
Free PMC Article

Activation of Tolloid-like 1 gene expression by the cardiac specific homeobox gene Nkx2-5.

Sabirzhanova I, Sabirzhanov B, Bjordahl J, Brandt J, Jay PY, Clark TG.

Dev Growth Differ. 2009 May;51(4):403-10.

PMID:
19366374
[PubMed - indexed for MEDLINE]

The 16th Asian Pacific Congress of Cardiology (APCC).

Jay PY.

IDrugs. 2008 Mar;11(3):181-3. No abstract available.

PMID:
18311653
[PubMed - indexed for MEDLINE]

HIV protease inhibitors that block GLUT4 precipitate acute, decompensated heart failure in a mouse model of dilated cardiomyopathy.

Hruz PW, Yan Q, Struthers H, Jay PY.

FASEB J. 2008 Jul;22(7):2161-7. Epub 2008 Feb 6.

PMID:
18256305
[PubMed - indexed for MEDLINE]
Free Article

Genetic wiring diagram of the cardiac conduction system.

Jay PY.

Circulation. 2007 Nov 27;116(22):2520-2. Review. No abstract available.

PMID:
18040037
[PubMed - indexed for MEDLINE]
Free Article

Mice lacking sister chromatid cohesion protein PDS5B exhibit developmental abnormalities reminiscent of Cornelia de Lange syndrome.

Zhang B, Jain S, Song H, Fu M, Heuckeroth RO, Erlich JM, Jay PY, Milbrandt J.

Development. 2007 Sep;134(17):3191-201. Epub 2007 Jul 25.

PMID:
17652350
[PubMed - indexed for MEDLINE]
Free Article

Molecular genetics of congenital diaphragmatic defects.

Bielinska M, Jay PY, Erlich JM, Mannisto S, Urban Z, Heikinheimo M, Wilson DB.

Ann Med. 2007;39(4):261-74. Review.

PMID:
17558598
[PubMed - indexed for MEDLINE]
Free PMC Article

PI3K(p110alpha) inhibitors as anti-cancer agents: minding the heart.

McMullen JR, Jay PY.

Cell Cycle. 2007 Apr 15;6(8):910-3. Epub 2007 Apr 7.

PMID:
17404510
[PubMed - indexed for MEDLINE]
Free Article

Protective effects of exercise and phosphoinositide 3-kinase(p110alpha) signaling in dilated and hypertrophic cardiomyopathy.

McMullen JR, Amirahmadi F, Woodcock EA, Schinke-Braun M, Bouwman RD, Hewitt KA, Mollica JP, Zhang L, Zhang Y, Shioi T, Buerger A, Izumo S, Jay PY, Jennings GL.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):612-7. Epub 2007 Jan 3.

PMID:
17202264
[PubMed - indexed for MEDLINE]
Free PMC Article

Impaired mesenchymal cell function in Gata4 mutant mice leads to diaphragmatic hernias and primary lung defects.

Jay PY, Bielinska M, Erlich JM, Mannisto S, Pu WT, Heikinheimo M, Wilson DB.

Dev Biol. 2007 Jan 15;301(2):602-14. Epub 2006 Oct 5.

PMID:
17069789
[PubMed - indexed for MEDLINE]
Free PMC Article

Dilated cardiomyopathy resulting from high-level myocardial expression of Cre-recombinase.

Buerger A, Rozhitskaya O, Sherwood MC, Dorfman AL, Bisping E, Abel ED, Pu WT, Izumo S, Jay PY.

J Card Fail. 2006 Jun;12(5):392-8.

PMID:
16762803
[PubMed - indexed for MEDLINE]

Haploinsufficiency of the cardiac transcription factor Nkx2-5 variably affects the expression of putative target genes.

Jay PY, Rozhitskaya O, Tarnavski O, Sherwood MC, Dorfman AL, Lu Y, Ueyama T, Izumo S.

FASEB J. 2005 Sep;19(11):1495-7. Epub 2005 Jun 22.

PMID:
15972800
[PubMed - indexed for MEDLINE]
Free Article

Absence of Msx2 does not affect cardiac conduction or rescue conduction defects associated with Nkx2-5 mutation.

Jay PY, Maguire CT, Wakimoto H, Izumo S, Berul CI.

J Cardiovasc Electrophysiol. 2005 Jan;16(1):82-5.

PMID:
15673394
[PubMed - indexed for MEDLINE]