Alan L Schwartz, PhD, MD

Commentary: physician-scientist attrition: stemming the tide through national networks for training and development.Schwartz AL.Acad Med. 2011 Sep;86(9):1071-2.

PMID:

21865903

[PubMed - indexed for MEDLINE]

Related citationsUbiquitin proteasome-dependent degradation of the transcriptional coactivator PGC-1{alpha} via the N-terminal pathway.Trausch-Azar J, Leone TC, Kelly DP, Schwartz AL.J Biol Chem. 2010 Dec 17;285(51):40192-200. Epub 2010 Aug 15.

PMID:

20713359

[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsLow-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9.Song H, Li Y, Lee J, Schwartz AL, Bu G.Cancer Res. 2009 Feb 1;69(3):879-86. Epub 2009 Jan 27.

PMID:

19176371

[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsTargeting proteins for destruction by the ubiquitin system: implications for human pathobiology.Schwartz AL, Ciechanover A.Annu Rev Pharmacol Toxicol. 2009;49:73-96. Review.

PMID:

18834306

[PubMed - indexed for MEDLINE]

Related citationsGlucocorticoids differentially regulate degradation of MyoD and Id1 by N-terminal ubiquitination to promote muscle protein catabolism.Sun L, Trausch-Azar JS, Muglia LJ, Schwartz AL.Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3339-44. Epub 2008 Feb 22.

PMID:

18296633

[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsIn vivo interactions of MyoD, Id1, and E2A proteins determined by acceptor photobleaching fluorescence resonance energy transfer.Lingbeck JM, Trausch-Azar JS, Ciechanover A, Schwartz AL.FASEB J. 2008 Jun;22(6):1694-701. Epub 2008 Jan 15.

PMID:

18198216

[PubMed - indexed for MEDLINE]

Free ArticleRelated citationsSlow endocytosis of the LDL receptor-related protein 1B: implications for a novel cytoplasmic tail conformation.Knisely JM, Li Y, Griffith JM, Geuze HJ, Schwartz AL, Bu G.Exp Cell Res. 2007 Sep 10;313(15):3298-307. Epub 2007 Jun 29.

PMID:

17658514

[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsE12 and E47 modulate cellular localization and proteasome-mediated degradation of MyoD and Id1.Lingbeck JM, Trausch-Azar JS, Ciechanover A, Schwartz AL.Oncogene. 2005 Sep 22;24(42):6376-84.

PMID:

16007194

[PubMed - indexed for MEDLINE]

Related citationsUbiquitin-proteasome-mediated degradation, intracellular localization, and protein synthesis of MyoD and Id1 during muscle differentiation.Sun L, Trausch-Azar JS, Ciechanover A, Schwartz AL.J Biol Chem. 2005 Jul 15;280(28):26448-56. Epub 2005 May 11.

PMID:

15888449

[PubMed - indexed for MEDLINE]

Free ArticleRelated citationsIndependent and cooperative roles of N-glycans and molecular chaperones in the folding and disulfide bond formation of the low-density lipoprotein (LDL) receptor-related protein.McCormick LM, Urade R, Arakaki Y, Schwartz AL, Bu G.Biochemistry. 2005 Apr 19;44(15):5794-803.

PMID:

15823038

[PubMed - indexed for MEDLINE]

Related citationsThe ubiquitin system: pathogenesis of human diseases and drug targeting.Ciechanover A, Schwartz AL.Biochim Biophys Acta. 2004 Nov 29;1695(1-3):3-17. Review.

PMID:

15571805

[PubMed - indexed for MEDLINE]

Related citationsLRP6 expression promotes cancer cell proliferation and tumorigenesis by altering beta-catenin subcellular distribution.Li Y, Lu W, He X, Schwartz AL, Bu G.Oncogene. 2004 Dec 2;23(56):9129-35.

PMID:

15516984

[PubMed - indexed for MEDLINE]

Related citationsThe tumor suppressor protein p16(INK4a) and the human papillomavirus oncoprotein-58 E7 are naturally occurring lysine-less proteins that are degraded by the ubiquitin system. Direct evidence for ubiquitination at the N-terminal residue.Ben-Saadon R, Fajerman I, Ziv T, Hellman U, Schwartz AL, Ciechanover A.J Biol Chem. 2004 Oct 1;279(40):41414-21. Epub 2004 Jul 14.

PMID:

15254040

[PubMed - indexed for MEDLINE]

Free ArticleRelated citationsUbiquitin-Proteasome-mediated degradation of Id1 is modulated by MyoD.Trausch-Azar JS, Lingbeck J, Ciechanover A, Schwartz AL.J Biol Chem. 2004 Jul 30;279(31):32614-9. Epub 2004 May 25.

PMID:

15163661

[PubMed - indexed for MEDLINE]

Free ArticleRelated citationsDegradation of the LDL receptor class 2 mutants is mediated by a proteasome-dependent pathway.Li Y, Lu W, Schwartz AL, Bu G.J Lipid Res. 2004 Jun;45(6):1084-91. Epub 2004 Mar 1.

PMID:

14993243

[PubMed - indexed for MEDLINE]

Free ArticleRelated citationsDegradation of the Id2 developmental regulator: targeting via N-terminal ubiquitination.Fajerman I, Schwartz AL, Ciechanover A.Biochem Biophys Res Commun. 2004 Feb 6;314(2):505-12.

PMID:

14733935

[PubMed - indexed for MEDLINE]

Related citationsCellular catabolism of lipid poor apolipoprotein E via cell surface LDL receptor-related protein.Narita M, Holtzman DM, Fagan AM, LaDu MJ, Yu L, Han X, Gross RW, Bu G, Schwartz AL.J Biochem. 2002 Nov;132(5):743-9.

PMID:

12417024

[PubMed - indexed for MEDLINE]

Free ArticleRelated citationsDeterminants of nuclear and cytoplasmic ubiquitin-mediated degradation of MyoD.Lingbeck JM, Trausch-Azar JS, Ciechanover A, Schwartz AL.J Biol Chem. 2003 Jan 17;278(3):1817-23. Epub 2002 Oct 22.

PMID:

12397066

[PubMed - indexed for MEDLINE]

Free ArticleRelated citationsProteasome regulates the delivery of LDL receptor-related protein into the degradation pathway.Melman L, Geuze HJ, Li Y, McCormick LM, Van Kerkhof P, Strous GJ, Schwartz AL, Bu G.Mol Biol Cell. 2002 Sep;13(9):3325-35.

PMID:

12221136

[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsLow density lipoprotein (LDL) receptor-related protein 1B impairs urokinase receptor regeneration on the cell surface and inhibits cell migration.Li Y, Knisely JM, Lu W, McCormick LM, Wang J, Henkin J, Schwartz AL, Bu G.J Biol Chem. 2002 Nov 1;277(44):42366-71. Epub 2002 Aug 22.

PMID:

12194987

[PubMed - indexed for MEDLINE]

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