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David H Gutmann, MD, PhD

David H Gutmann, MD, PhD

Dr. Gutmann directs the Neurofibromatosis Program. He is an internationally-recognized expert in neurofibromatosis, and was a member of the research group that identified the entire NF1 gene. He is the Donald O. Schnuck Family Professor of Neurology and Director of the Neurofibromatosis Center at Washington University School of Medicine and Co-Director of the Neuro-Oncology Program at the Siteman Cancer Center and Washington University School Medicine. Patient records and any correspondence should be sent to: 660 South Euclid Avenue, Campus Box 8111, St. Louis, MO 63110
Department Of Neurology
53
Male
Neurology-Pediatric - certified
Neurology - certified
Siteman Cancer Center
St. Louis Children's Hospital
Barnes-Jewish Hospital

For Patients:
To request an appointment, call 800.678.KIDS (5437) or fill out our online form.

For Referring Physicians:
To refer a patient, call Children's Direct at 800.678.HELP (4357).

For Patients:
To request an appointment, call 800.678.KIDS (5437) or fill out our online form.

For Referring Physicians:
To refer a patient, call Children's Direct at 800.678.HELP (4357).

 

  Public transportation available |   Handicap accessible
1 Children's Place
Suite 2D
St. Louis, MO 63110
314.454.6120
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Education

Medical School: University of Michigan Ann Arbor
Internship: University of Pennsylvania Philadelphia Pennsylvania
Residency: University of Pennsylvania Philadelphia Pennsylvania
Fellowship: University of Michigan Ann Arbor

Health Plans Accepted

Aetna Medicare HMO
Aetna Medicare Open Access (HMO/POS
Aetna PPO
Anthem BCBS Blue Access Choice PPO
Anthem BCBS Blue Access PPO
BCBS of IL HMO
BCBS of IL PPO
Beech Street/Capp Care PPO
Best Doctors Inc
Cigna Open Access HMO/POS
Cigna PPO
Community Care Network PPO
Coventry Advantra HMO/POS-Medicare
Coventry ASO
Coventry Gold Advantage - Medicare
Coventry HMO/POS
Coventry/Coventry One PPO
Essence Advantage & Advantage Plus
First Health
Great-West HMO/POS
Great-West Open Access
Great-West PPO
Health Alliance HMO & PPO
Healthlink Open Access/HMO/POS
Healthlink PPO
HFN Inc. PPO
Humana Choice PPO - Medicare
Humana Gold Choice PFFS - Medicare
Humana Gold Plus HMO - Medicare
Humana POS-Medicare
Humana PPO/ChoiceCare Network
Illinois Public Aid/Health Connect
Medicare
Mercy Health Plan HMO/POS
Mercy Health Plan PPO
MO Medicaid Secondary to Medicare
MultiPlan PPO
Primrose Tertiary/Quarternary
Private Health Care Systems PPO
Tricare/Triwest Prime HMO/POS
Tricare/Triwest Standard/ Extra PPO
UHC/AARP MCARE Complete Choice PPO
UHC/AARP MCARE Complete HMO
UHC/AARP MCARE CompleteEssen. HMO
UHC/AARP MCARE Dual Complete
Union Pacific RR Emp. Health System
United Healthcare Choice/Choice+
United Healthcare PPO/ Options
United Healthcare Select/Select+POS
USA Managed Care Org
Verify insurance with office
Worker's Compensation

Low-grade gliomas as neurodevelopmental disorders: Insights from mouse models of neurofibromatosis-1.Thangarajh M, Gutmann DH.Neuropathol Appl Neurobiol. 2011 Oct 28. doi: 10.1111/j.1365-2990.2011.01230.x. [Epub ahead of print]

PMID:
22035280
[PubMed - as supplied by publisher]

Related citationsPET imaging for attention deficit preclinical drug testing in neurofibromatosis-1 mice.Brown JA, Xu J, Diggs-Andrews KA, Wozniak DF, Mach RH, Gutmann DH.Exp Neurol. 2011 Dec;232(2):333-8. Epub 2011 Sep 22.

PMID:
21963652
[PubMed - indexed for MEDLINE]

Related citationsNeurofibromatosis-1 heterozygosity impairs CNS neuronal morphology in a cAMP/PKA/ROCK-dependent manner.Brown JA, Diggs-Andrews KA, Gianino SM, Gutmann DH.Mol Cell Neurosci. 2011 Aug 26. [Epub ahead of print]

PMID:
21903164
[PubMed - as supplied by publisher]

Related citationsNeurofibromatosis-1 regulates mTOR-mediated astrocyte growth and glioma formation in a TSC/Rheb-independent manner.Banerjee S, Crouse NR, Emnett RJ, Gianino SM, Gutmann DH.Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15996-6001. Epub 2011 Sep 6.

PMID:
21896734
[PubMed - indexed for MEDLINE]

Related citationsIntegrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis.Stenzel D, Lundkvist A, Sauvaget D, Busse M, Graupera M, van der Flier A, Wijelath ES, Murray J, Sobel M, Costell M, Takahashi S, Fässler R, Yamaguchi Y, Gutmann DH, Hynes RO, Gerhardt H.Development. 2011 Oct;138(20):4451-63. Epub 2011 Aug 31.

PMID:
21880786
[PubMed - indexed for MEDLINE]

Related citationsIdentification of transcriptional regulatory networks specific to pilocytic astrocytoma.Deshmukh H, Yu J, Shaik J, MacDonald TJ, Perry A, Payton JE, Gutmann DH, Watson MA, Nagarajan R.BMC Med Genomics. 2011 Jul 11;4:57.

PMID:
21745356
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsReport from the fifth National Cancer Institute Mouse Models of Human Cancers Consortium Nervous System Tumors Workshop.Gutmann DH, Stiles CD, Lowe SW, Bollag GE, Furnari FB, Charest AL.Neuro Oncol. 2011 Jul;13(7):692-9. Review.

PMID:
21727208
[PubMed - indexed for MEDLINE]

Related citationsComparative characterization of the human and mouse third ventricle germinal zones.Dahiya S, Lee da Y, Gutmann DH.J Neuropathol Exp Neurol. 2011 Jul;70(7):622-33.

PMID:
21666496
[PubMed - indexed for MEDLINE]

Related citationsArray-based comparative genomic hybridization identifies CDK4 and FOXM1 alterations as independent predictors of survival in malignant peripheral nerve sheath tumor.Yu J, Deshmukh H, Payton JE, Dunham C, Scheithauer BW, Tihan T, Prayson RA, Guha A, Bridge JA, Ferner RE, Lindberg GM, Gutmann RJ, Emnett RJ, Salavaggione L, Gutmann DH, Nagarajan R, Watson MA, Perry A.Clin Cancer Res. 2011 Apr 1;17(7):1924-34. Epub 2011 Feb 16.

PMID:
21325289
[PubMed - indexed for MEDLINE]

Related citationsRethinking pediatric gliomas as developmental brain abnormalities.Crouse NR, Dahiya S, Gutmann DH.Curr Top Dev Biol. 2011;94:283-308. Review.

PMID:
21295690
[PubMed - indexed for MEDLINE]

Related citationsInterpreting mammalian target of rapamycin and cell growth inhibition in a genetically engineered mouse model of Nf1-deficient astrocytes.Banerjee S, Gianino SM, Gao F, Christians U, Gutmann DH.Mol Cancer Ther. 2011 Feb;10(2):279-91. Epub 2011 Jan 7.

PMID:
21216928
[PubMed - indexed for MEDLINE]

Related citationsIdentification of gene markers associated with aggressive meningioma by filtering across multiple sets of gene expression arrays.Stuart JE, Lusis EA, Scheck AC, Coons SW, Lal A, Perry A, Gutmann DH.J Neuropathol Exp Neurol. 2011 Jan;70(1):1-12.

PMID:
21157382
[PubMed - indexed for MEDLINE]

Related citationsNeurofibromatosis-1 heterozygosity increases microglia in a spatially and temporally restricted pattern relevant to mouse optic glioma formation and growth.Simmons GW, Pong WW, Emnett RJ, White CR, Gianino SM, Rodriguez FJ, Gutmann DH.J Neuropathol Exp Neurol. 2011 Jan;70(1):51-62.

PMID:
21157378
[PubMed - indexed for MEDLINE]

Related citationsSubtypes of medulloblastoma have distinct developmental origins.Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ.Nature. 2010 Dec 23;468(7327):1095-9. Epub 2010 Dec 8.

PMID:
21150899
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsTsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex.Zeng LH, Rensing NR, Zhang B, Gutmann DH, Gambello MJ, Wong M.Hum Mol Genet. 2011 Feb 1;20(3):445-54. Epub 2010 Nov 9.

PMID:
21062901
[PubMed - indexed for MEDLINE]

Related citationsAstrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice.Wang L, Gutmann DH, Roos RP.Hum Mol Genet. 2011 Jan 15;20(2):286-93. Epub 2010 Oct 20.

PMID:
20962037
[PubMed - indexed for MEDLINE]

Related citationsPostoperative imaging surveillance in pediatric pilocytic astrocytomas.Dorward IG, Luo J, Perry A, Gutmann DH, Mansur DB, Rubin JB, Leonard JR.J Neurosurg Pediatr. 2010 Oct;6(4):346-52.

PMID:
20887107
[PubMed - indexed for MEDLINE]

Related citationsNeurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner.Lee da Y, Yeh TH, Emnett RJ, White CR, Gutmann DH.Genes Dev. 2010 Oct 15;24(20):2317-29. Epub 2010 Sep 28.

PMID:
20876733
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsReduced striatal dopamine underlies the attention system dysfunction in neurofibromatosis-1 mutant mice.Brown JA, Emnett RJ, White CR, Yuede CM, Conyers SB, O'Malley KL, Wozniak DF, Gutmann DH.Hum Mol Genet. 2010 Nov 15;19(22):4515-28. Epub 2010 Sep 7.

PMID:
20826448
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsAstrocyte-derived vascular endothelial growth factor stabilizes vessels in the developing retinal vasculature.Scott A, Powner MB, Gandhi P, Clarkin C, Gutmann DH, Johnson RS, Ferrara N, Fruttiger M.PLoS One. 2010 Jul 29;5(7):e11863.

PMID:
20686684
[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsView More Publications