Christina A Gurnett, MD

Variants in genes that encode muscle contractile proteins influence risk for isolated clubfoot.Weymouth KS, Blanton SH, Bamshad MJ, Beck AE, Alvarez C, Richards S, Gurnett CA, Dobbs MB, Barnes D, Mitchell LE, Hecht JT.Am J Med Genet A. 2011 Sep;155A(9):2170-9. doi: 10.1002/ajmg.a.34167. Epub 2011 Aug 10.

PMID:

21834041

[PubMed - in process]

Related citationsGenetics of clubfoot.Dobbs MB, Gurnett CA.J Pediatr Orthop B. 2012 Jan;21(1):7-9.

PMID:

21817922

[PubMed - in process]

Related citationsPitx1 haploinsufficiency causes clubfoot in humans and a clubfoot-like phenotype in mice.Alvarado DM, McCall K, Aferol H, Silva MJ, Garbow JR, Spees WM, Patel T, Siegel M, Dobbs MB, Gurnett CA.Hum Mol Genet. 2011 Oct 15;20(20):3943-52. Epub 2011 Jul 20.

PMID:

21775501

[PubMed - in process]

Related citationsCommon polymorphisms in human lysyl oxidase genes are not associated with the adolescent idiopathic scoliosis phenotype.McGregor TL, Gurnett CA, Dobbs MB, Wise CA, Morcuende JA, Morgan TM, Menon R, Muglia LJ.BMC Med Genet. 2011 Jul 8;12:92.

PMID:

21740577

[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsCopy number variants and infantile spasms: evidence for abnormalities in ventral forebrain development and pathways of synaptic function.Paciorkowski AR, Thio LL, Rosenfeld JA, Gajecka M, Gurnett CA, Kulkarni S, Chung WK, Marsh ED, Gentile M, Reggin JD, Wheless JW, Balasubramanian S, Kumar R, Christian SL, Marini C, Guerrini R, Maltsev N, Shaffer LG, Dobyns WB.Eur J Hum Genet. 2011 Dec;19(12):1238-45. doi: 10.1038/ejhg.2011.121. Epub 2011 Jun 22.

PMID:

21694734

[PubMed - in process]

Related citationsRe: Ward K, Ogilvie JW, Singleton MV, et al. Validation of DNA-based prognostic testing to predict spinal curve progression in adolescent idiopathic scoliosis. Spine 2010;35:E1455-64.Dobbs MB, Gurnett CA.Spine (Phila Pa 1976). 2011 Jul 1;36(15):1257; author reply 1257. No abstract available.

PMID:

21691188

[PubMed - indexed for MEDLINE]

Related citationsExome sequencing identifies an MYH3 mutation in a family with distal arthrogryposis type 1.Alvarado DM, Buchan JG, Gurnett CA, Dobbs MB.J Bone Joint Surg Am. 2011 Jun 1;93(11):1045-50.

PMID:

21531865

[PubMed - indexed for MEDLINE]

Related citationsVoltage-gated potassium channel KCNV2 (Kv8.2) contributes to epilepsy susceptibility.Jorge BS, Campbell CM, Miller AR, Rutter ED, Gurnett CA, Vanoye CG, George AL Jr, Kearney JA.Proc Natl Acad Sci U S A. 2011 Mar 29;108(13):5443-8. Epub 2011 Mar 14.

PMID:

21402906

[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsGenome-wide association studies of adolescent idiopathic scoliosis suggest candidate susceptibility genes.Sharma S, Gao X, Londono D, Devroy SE, Mauldin KN, Frankel JT, Brandon JM, Zhang D, Li QZ, Dobbs MB, Gurnett CA, Grant SF, Hakonarson H, Dormans JP, Herring JA, Gordon D, Wise CA.Hum Mol Genet. 2011 Apr 1;20(7):1456-66. Epub 2011 Jan 7.

PMID:

21216876

[PubMed - indexed for MEDLINE]

Related citationsVascular abnormalities correlate with decreased soft tissue volumes in idiopathic clubfoot.Merrill LJ, Gurnett CA, Siegel M, Sonavane S, Dobbs MB.Clin Orthop Relat Res. 2011 May;469(5):1442-9. Epub 2010 Nov 2.

PMID:

21042891

[PubMed - indexed for MEDLINE]

Related citationsEvaluation of GPR50, hMel-1B, and ROR-alpha melatonin-related receptors and the etiology of adolescent idiopathic scoliosis.Shyy W, Wang K, Gurnett CA, Dobbs MB, Miller NH, Wise C, Sheffield VC, Morcuende JA.J Pediatr Orthop. 2010 Sep;30(6):539-43.

PMID:

20733416

[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsSkeletal muscle abnormalities and genetic factors related to vertical talus.Merrill LJ, Gurnett CA, Connolly AM, Pestronk A, Dobbs MB.Clin Orthop Relat Res. 2011 Apr;469(4):1167-74. Epub 2010 Jul 20.

PMID:

20645034

[PubMed - indexed for MEDLINE]

Related citationsFamilial isolated clubfoot is associated with recurrent chromosome 17q23.1q23.2 microduplications containing TBX4.Alvarado DM, Aferol H, McCall K, Huang JB, Techy M, Buchan J, Cady J, Gonzales PR, Dobbs MB, Gurnett CA.Am J Hum Genet. 2010 Jul 9;87(1):154-60.

PMID:

20598276

[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsGenome-wide copy number variation in epilepsy: novel susceptibility loci in idiopathic generalized and focal epilepsies.Mefford HC, Muhle H, Ostertag P, von Spiczak S, Buysse K, Baker C, Franke A, Malafosse A, Genton P, Thomas P, Gurnett CA, Schreiber S, Bassuk AG, Guipponi M, Stephani U, Helbig I, Eichler EE.PLoS Genet. 2010 May 20;6(5):e1000962.

PMID:

20502679

[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsMyosin binding protein C1: a novel gene for autosomal dominant distal arthrogryposis type 1.Gurnett CA, Desruisseau DM, McCall K, Choi R, Meyer ZI, Talerico M, Miller SE, Ju JS, Pestronk A, Connolly AM, Druley TE, Weihl CC, Dobbs MB.Hum Mol Genet. 2010 Apr 1;19(7):1165-73. Epub 2010 Jan 2.

PMID:

20045868

[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsAltered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot.Ester AR, Weymouth KS, Burt A, Wise CA, Scott A, Gurnett CA, Dobbs MB, Blanton SH, Hecht JT.Am J Med Genet A. 2009 Dec;149A(12):2745-52.

PMID:

19938081

[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsPilocytic astrocytoma in a child with Noonan syndrome.Schuettpelz LG, McDonald S, Whitesell K, Desruisseau DM, Grange DK, Gurnett CA, Wilson DB.Pediatr Blood Cancer. 2009 Dec;53(6):1147-9.

PMID:

19621452

[PubMed - indexed for MEDLINE]

Related citationsDICER1 mutations in familial pleuropulmonary blastoma.Hill DA, Ivanovich J, Priest JR, Gurnett CA, Dehner LP, Desruisseau D, Jarzembowski JA, Wikenheiser-Brokamp KA, Suarez BK, Whelan AJ, Williams G, Bracamontes D, Messinger Y, Goodfellow PJ.Science. 2009 Aug 21;325(5943):965. Epub 2009 Jun 25.

PMID:

19556464

[PubMed - indexed for MEDLINE]

Free PMC ArticleRelated citationsEarly results of the Ponseti method for the treatment of clubfoot associated with myelomeningocele.Gerlach DJ, Gurnett CA, Limpaphayom N, Alaee F, Zhang Z, Porter K, Kirchhofer M, Smyth MD, Dobbs MB.J Bone Joint Surg Am. 2009 Jun;91(6):1350-9.

PMID:

19487512

[PubMed - indexed for MEDLINE]

Related citationsUpdate on clubfoot: etiology and treatment.Dobbs MB, Gurnett CA.Clin Orthop Relat Res. 2009 May;467(5):1146-53. Epub 2009 Feb 18. Review.

PMID:

19224303

[PubMed - indexed for MEDLINE]

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