For Patients:
To request an appointment, call 800.678.KIDS (5437) or fill out our online form.
For Referring Physicians:
To refer a patient, call Children's Direct at 800.678.HELP (4357).
Liu Lin Thio, MD
For Patients:
To request an appointment, call 800.678.KIDS (5437) or fill out our online form.
For Referring Physicians:
To refer a patient, call Children's Direct at 800.678.HELP (4357).

Suite 2D
Saint Louis, MO 63110
314.454.6120
Education
Internship: St. Louis Children's Hospital
Residency: St. Louis Children's Hospital
Fellowship: St. Louis Children's Hospital
Fellowship: Children's Hospital Boston
Health Plans Accepted
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Admar |
Aetna HMO/Open Access |
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Aetna Managed Choice POS |
Aetna PPO |
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BCBS of IL PPO |
BCBS/Anthem(Blue Access Choice PPO |
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BCBS/Anthem(Blue Access PPO) |
Beech Street/Capp Care PPO |
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Cigna Open Access HMO/POS |
Cigna PPO |
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CMR (Care Management Resources) |
Community Care Network PPO |
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CorVel PPO |
Coventry Advantra HMO - Medicare |
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Coventry HMO/POS |
Coventry PPO |
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First Health |
Great-West HMO/POS |
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Great-West Open Access |
Great-West PPO |
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Health Alliance HMO & PPO |
Healthlink Open Access/HMO/POS |
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Healthlink PPO |
Home State-MC+ |
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Humana PPO/ChoiceCare Network |
Illinois Public Aid/Health Connect |
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IPA Secondary to Medicare |
Mail Handlers/CNA PPO |
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Medicaid MO/ Missouri HealthNet |
Medicare |
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Mercy Health Plan PPO |
MO Medicaid Secondary to Medicare |
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MultiPlan PPO |
PPO Next/HealthStar |
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Primrose Tertiary/Quarternary |
Private Health Care Systems PPO |
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ProAmerica PPO |
Providers Network of America |
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Tricare/Triwest Prime HMO/POS |
Tricare/Triwest Standard/ Extra PPO |
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Union Pacific RR Emp. Health System |
United Healthcare Choice/Choice+ |
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United Healthcare PPO/ Options |
United Healthcare Select/Select+POS |
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United Payors & Provider |
USA Managed Care Org |
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Wellborn HMO |
Genetic and biologic classification of infantile spasms.Paciorkowski AR, Thio LL, Dobyns WB.Pediatr Neurol. 2011 Dec;45(6):355-67.
- PMID:
- 22114996
- [PubMed - in process]
Related citationsHypothalamic hormones and metabolism.Thio LL.Epilepsy Res. 2011 Aug 17. [Epub ahead of print]
- PMID:
- 21856125
- [PubMed - as supplied by publisher]
Related citationsCopy number variants and infantile spasms: evidence for abnormalities in ventral forebrain development and pathways of synaptic function.Paciorkowski AR, Thio LL, Rosenfeld JA, Gajecka M, Gurnett CA, Kulkarni S, Chung WK, Marsh ED, Gentile M, Reggin JD, Wheless JW, Balasubramanian S, Kumar R, Christian SL, Marini C, Guerrini R, Maltsev N, Shaffer LG, Dobyns WB.Eur J Hum Genet. 2011 Dec;19(12):1238-45. doi: 10.1038/ejhg.2011.121. Epub 2011 Jun 22.
- PMID:
- 21694734
- [PubMed - in process]
Related citationsThe ketogenic diet inhibits the mammalian target of rapamycin (mTOR) pathway.McDaniel SS, Rensing NR, Thio LL, Yamada KA, Wong M.Epilepsia. 2011 Mar;52(3):e7-11. doi: 10.1111/j.1528-1167.2011.02981.x. Epub 2011 Mar 3.
- PMID:
- 21371020
- [PubMed - indexed for MEDLINE]
Related citationsA ketogenic diet does not impair rat behavior or long-term potentiation.Thio LL, Rensing N, Maloney S, Wozniak DF, Xiong C, Yamada KA.Epilepsia. 2010 Aug;51(8):1619-23.
- PMID:
- 20132289
- [PubMed - indexed for MEDLINE]
Free PMC ArticleRelated citationsEpilepsy in infancy: answering the call.Thio LL, Dodson WE.Neurology. 2010 Mar 2;74(9):708-9. Epub 2010 Jan 27. No abstract available.
- PMID:
- 20107140
- [PubMed - indexed for MEDLINE]
Related citationsThe glycine transport inhibitor sarcosine is an inhibitory glycine receptor agonist.Zhang HX, Lyons-Warren A, Thio LL.Neuropharmacology. 2009 Oct-Nov;57(5-6):551-5. Epub 2009 Jul 18.
- PMID:
- 19619564
- [PubMed - indexed for MEDLINE]
Free PMC ArticleRelated citationsThe glycine transport inhibitor sarcosine is an NMDA receptor co-agonist that differs from glycine.Zhang HX, Hyrc K, Thio LL.J Physiol. 2009 Jul 1;587(Pt 13):3207-20. Epub 2009 May 11.
- PMID:
- 19433577
- [PubMed - indexed for MEDLINE]
Free PMC ArticleRelated citationsIncreased severity of pentylenetetrazol induced seizures in leptin deficient ob/ob mice.Erbayat-Altay E, Yamada KA, Wong M, Thio LL.Neurosci Lett. 2008 Mar 12;433(2):82-6. Epub 2007 Dec 28.
- PMID:
- 18241989
- [PubMed - indexed for MEDLINE]
Related citationsLeptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents.Xu L, Rensing N, Yang XF, Zhang HX, Thio LL, Rothman SM, Weisenfeld AE, Wong M, Yamada KA.J Clin Invest. 2008 Jan;118(1):272-80.
- PMID:
- 18097472
- [PubMed - indexed for MEDLINE]
Free PMC ArticleRelated citationsZinc enhances the inhibitory effects of strychnine-sensitive glycine receptors in mouse hippocampal neurons.Zhang HX, Thio LL.J Neurophysiol. 2007 Dec;98(6):3666-76. Epub 2007 Oct 3.
- PMID:
- 17913992
- [PubMed - indexed for MEDLINE]
Free ArticleRelated citationsLeptin contributes to slower weight gain in juvenile rodents on a ketogenic diet.Thio LL, Erbayat-Altay E, Rensing N, Yamada KA.Pediatr Res. 2006 Oct;60(4):413-7. Epub 2006 Aug 28.
- PMID:
- 16940251
- [PubMed - indexed for MEDLINE]
Related citationsRotational vestibular epilepsy from the temporo-parieto-occipital junction.Jaffe SL, DellaBadia J, Erbayat-Altay E, Thio LL.Neurology. 2006 Jul 25;67(2):368; author reply 368. No abstract available.
- PMID:
- 16864851
- [PubMed - indexed for MEDLINE]
Related citationsKetogenic diet reduces hypoglycemia-induced neuronal death in young rats.Yamada KA, Rensing N, Thio LL.Neurosci Lett. 2005 Sep 16;385(3):210-4.
- PMID:
- 15975714
- [PubMed - indexed for MEDLINE]
Related citationsAcute vigabatrin retinotoxicity in albino rats depends on light but not GABA.Izumi Y, Ishikawa M, Benz AM, Izumi M, Zorumski CF, Thio LL.Epilepsia. 2004 Sep;45(9):1043-8.
- PMID:
- 15329067
- [PubMed - indexed for MEDLINE]
Related citationsDifferential presynaptic modulation of excitatory and inhibitory autaptic currents in cultured hippocampal neurons.Thio LL, Yamada KA.Brain Res. 2004 Jun 25;1012(1-2):22-8.
- PMID:
- 15158157
- [PubMed - indexed for MEDLINE]
Related citationsEffects of seven clinically important antiepileptic drugs on inhibitory glycine receptor currents in hippocampal neurons.Karkar KM, Thio LL, Yamada KA.Epilepsy Res. 2004 Jan;58(1):27-35.
- PMID:
- 15066672
- [PubMed - indexed for MEDLINE]
Related citationsBenzodiazepines block alpha2-containing inhibitory glycine receptors in embryonic mouse hippocampal neurons.Thio LL, Shanmugam A, Isenberg K, Yamada K.J Neurophysiol. 2003 Jul;90(1):89-99. Epub 2003 Mar 26.
- PMID:
- 12660352
- [PubMed - indexed for MEDLINE]
Free ArticleRelated citationsThe estrogen receptor is not essential for all estrogen neuroprotection: new evidence from a new analog.Xia S, Cai ZY, Thio LL, Kim-Han JS, Dugan LL, Covey DF, Rothman SM.Neurobiol Dis. 2002 Apr;9(3):282-93.
- PMID:
- 11950274
- [PubMed - indexed for MEDLINE]











