For Patients:
To request an appointment, call 800.678.KIDS (5437) or fill out our online form.
For Referring Physicians:
To refer a patient, call Children's Direct at 800.678.HELP (4357).
Robert Heuckeroth, MD
*Pediatrics - certified
For Patients:
To request an appointment, call 800.678.KIDS (5437) or fill out our online form.
For Referring Physicians:
To refer a patient, call Children's Direct at 800.678.HELP (4357).

2Nd Floor Suite C
Saint Louis, MO 63110
314.454.6173
Education
Internship: St. Louis Children's Hospital
Residency: St. Louis Children's Hospital
Fellowship: St. Louis Children's Hospital
Health Plans Accepted
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Admar |
Aetna PPO |
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BCBS of IL HMO |
BCBS of IL PPO |
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BCBS/Anthem(Blue Access Choice PPO |
BCBS/Anthem(Blue Access PPO) |
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Cigna Open Access HMO/POS |
Cigna PPO |
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CMR (Care Management Resources) |
CorVel PPO |
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Coventry HMO/POS (formerly GHP) |
Coventry PPO (formerly GHP) |
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First Health |
Great Rivers Network |
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Health Alliance HMO & PPO |
Healthlink Open Access/HMO/POS |
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Healthlink PPO |
Home State-MC+ |
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Humana PPO/ChoiceCare Network |
Illinois Public Aid/Health Connect |
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IPA Secondary to Medicare |
Medicaid MO/ Missouri HealthNet |
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Medicare |
Preferred Plan of MO PPO/Takecare |
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Primrose Tertiary/Quarternary |
Private Health Care Systems PPO |
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ProAmerica PPO |
Providers Network of America |
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Union Pacific RR Emp. Health System |
United Healthcare Choice/Choice+ |
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United Healthcare PPO/ Options |
United Healthcare Select/Select+POS |
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United Payors & Provider |
USA Managed Care Org |
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Wellborn HMO |
Differential regional and subtype-specific vulnerability of enteric neurons to mitochondrial dysfunction.Viader A, Wright-Jin EC, Vohra BP, Heuckeroth RO, Milbrandt J.PLoS One. 2011;6(11):e27727. Epub 2011 Nov 16.
- PMID:
- 22110743
- [PubMed - in process]
Free PMC ArticleRelated citationsIn Reply To: Slow Growth: Do Not Forget Thyroid.Bennett WE Jr, Heuckeroth RO.J Pediatr Gastroenterol Nutr. 2011 Nov 18. [Epub ahead of print] No abstract available.
- PMID:
- 22108338
- [PubMed - as supplied by publisher]
Related citationsHypothyroidism is a rare cause of isolated constipation: 5-year review of all thyroid tests in a pediatric gastroenterology office.Bennett WE Jr, Heuckeroth RO.J Pediatr Gastroenterol Nutr. 2011 Oct 3. [Epub ahead of print]
- PMID:
- 21975961
- [PubMed - as supplied by publisher]
Related citationsSerum markers may distinguish biliary atresia from other forms of neonatal cholestasis.Wang H, Malone JP, Gilmore PE, Davis AE, Magee JC, Townsend RR, Heuckeroth RO.J Pediatr Gastroenterol Nutr. 2010 Apr;50(4):411-6.
- PMID:
- 20216099
- [PubMed - indexed for MEDLINE]
Free PMC ArticleRelated citationsOrganotypic specificity of key RET adaptor-docking sites in the pathogenesis of neurocristopathies and renal malformations in mice.Jain S, Knoten A, Hoshi M, Wang H, Vohra B, Heuckeroth RO, Milbrandt J.J Clin Invest. 2010 Mar 1;120(3):778-90. doi: 10.1172/JCI41619. Epub 2010 Feb 15.
- PMID:
- 20160347
- [PubMed - indexed for MEDLINE]
Free PMC ArticleRelated citationsVitamin A facilitates enteric nervous system precursor migration by reducing Pten accumulation.Fu M, Sato Y, Lyons-Warren A, Zhang B, Kane MA, Napoli JL, Heuckeroth RO.Development. 2010 Feb;137(4):631-40.
- PMID:
- 20110328
- [PubMed - indexed for MEDLINE]
Free PMC ArticleRelated citationsThe timing and location of glial cell line-derived neurotrophic factor expression determine enteric nervous system structure and function.Wang H, Hughes I, Planer W, Parsadanian A, Grider JR, Vohra BP, Keller-Peck C, Heuckeroth RO.J Neurosci. 2010 Jan 27;30(4):1523-38.
- PMID:
- 20107080
- [PubMed - indexed for MEDLINE]
Free PMC ArticleRelated citationsDosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies.Zhang B, Chang J, Fu M, Huang J, Kashyap R, Salavaggione E, Jain S, Kulkarni S, Deardorff MA, Uzielli ML, Dorsett D, Beebe DC, Jay PY, Heuckeroth RO, Krantz I, Milbrandt J.PLoS One. 2009;4(5):e5232. Epub 2009 May 1. Erratum in: PLoS One. 2009;4(5). doi: 10.1371/annotation/ea5b7eb5-5087-448a-8325-c8efff1f54d9. Shashikant, Kulkarni [corrected to Kulkarni, Shashikant].
- PMID:
- 19412548
- [PubMed - indexed for MEDLINE]
Free PMC ArticleRelated citationsRetinoic acid regulates murine enteric nervous system precursor proliferation, enhances neuronal precursor differentiation, and reduces neurite growth in vitro.Sato Y, Heuckeroth RO.Dev Biol. 2008 Aug 1;320(1):185-98. Epub 2008 May 20.
- PMID:
- 18561907
- [PubMed - indexed for MEDLINE]
Free PMC ArticleRelated citationsProtein kinase Czeta and glycogen synthase kinase-3beta control neuronal polarity in developing rodent enteric neurons, whereas SMAD specific E3 ubiquitin protein ligase 1 promotes neurite growth but does not influence polarity.Vohra BP, Fu M, Heuckeroth RO.J Neurosci. 2007 Aug 29;27(35):9458-68.
- PMID:
- 17728459
- [PubMed - indexed for MEDLINE]
Free PMC ArticleRelated citationsMice lacking sister chromatid cohesion protein PDS5B exhibit developmental abnormalities reminiscent of Cornelia de Lange syndrome.Zhang B, Jain S, Song H, Fu M, Heuckeroth RO, Erlich JM, Jay PY, Milbrandt J.Development. 2007 Sep;134(17):3191-201. Epub 2007 Jul 25.
- PMID:
- 17652350
- [PubMed - indexed for MEDLINE]
Free ArticleRelated citationsPAI-1 deficiency reduces liver fibrosis after bile duct ligation in mice through activation of tPA.Wang H, Zhang Y, Heuckeroth RO.FEBS Lett. 2007 Jun 26;581(16):3098-104. Epub 2007 May 29.
- PMID:
- 17561000
- [PubMed - indexed for MEDLINE]
Related citationsTissue-type plasminogen activator deficiency exacerbates cholestatic liver injury in mice.Wang H, Zhang Y, Heuckeroth RO.Hepatology. 2007 Jun;45(6):1527-37.
- PMID:
- 17538930
- [PubMed - indexed for MEDLINE]
Related citationsReduced endothelin converting enzyme-1 and endothelin-3 mRNA in the developing bowel of male mice may increase expressivity and penetrance of Hirschsprung disease-like distal intestinal aganglionosis.Vohra BP, Planer W, Armon J, Fu M, Jain S, Heuckeroth RO.Dev Dyn. 2007 Jan;236(1):106-17.
- PMID:
- 17131407
- [PubMed - indexed for MEDLINE]
Free ArticleRelated citationsBMP signaling regulates murine enteric nervous system precursor migration, neurite fasciculation, and patterning via altered Ncam1 polysialic acid addition.Fu M, Vohra BP, Wind D, Heuckeroth RO.Dev Biol. 2006 Nov 1;299(1):137-50. Epub 2006 Jul 21.
- PMID:
- 16952347
- [PubMed - indexed for MEDLINE]
Free PMC ArticleRelated citationsDifferential gene expression and functional analysis implicate novel mechanisms in enteric nervous system precursor migration and neuritogenesis.Vohra BP, Tsuji K, Nagashimada M, Uesaka T, Wind D, Fu M, Armon J, Enomoto H, Heuckeroth RO.Dev Biol. 2006 Oct 1;298(1):259-71. Epub 2006 Jun 27.
- PMID:
- 16904662
- [PubMed - indexed for MEDLINE]
Free PMC ArticleRelated citationsGetting to the guts of enteric nervous system development.Heuckeroth RO, Pachnis V.Development. 2006 Jun;133(12):2287-90.
- PMID:
- 16720873
- [PubMed - indexed for MEDLINE]
Free ArticleRelated citationsTranscriptional profiling after bile duct ligation identifies PAI-1 as a contributor to cholestatic injury in mice.Wang H, Vohra BP, Zhang Y, Heuckeroth RO.Hepatology. 2005 Nov;42(5):1099-108.
- PMID:
- 16250054
- [PubMed - indexed for MEDLINE]
Related citationsEnteric neuroblasts require the phosphatidylinositol 3-kinase/Akt/Forkhead pathway for GDNF-stimulated survival.Srinivasan S, Anitha M, Mwangi S, Heuckeroth RO.Mol Cell Neurosci. 2005 May;29(1):107-19.
- PMID:
- 15866051
- [PubMed - indexed for MEDLINE]
Related citationsA human yeast artificial chromosome containing the multiple endocrine neoplasia type 2B Ret mutation does not induce medullary thyroid carcinoma but does support the growth of kidneys and partially rescues enteric nervous system development in Ret-deficient mice.Skinner MA, Kalyanaraman S, Safford SD, Heuckeroth RO, Tourtellotte W, Goyeau D, Goodfellow P, Milbrandt JD, Freemerman A.Am J Pathol. 2005 Jan;166(1):265-74.
- PMID:
- 15632018
- [PubMed - indexed for MEDLINE]











