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Zoe, a St. Louis Children’s patient, blowing bubbles outside.
Zoe, a St. Louis Children’s patient, blowing bubbles outside.
Close-up of St. Louis Children’s patient and parent.

A REVOLUTIONARY RESEARCH HUB

Genes, the building blocks of human development, guide the body’s functions and structures — from readily visible physical traits to complex processes we never consciously notice. The body’s immunity is rooted in that genetic makeup — but for about 1% of the population, errors in the genetic code cause immune systems to function poorly, attacking the body’s own cells and organs as if they were infectious. For children with immunodeficiency disorders, it means that everyday activities like going to school, playing sports or spending time with friends can carry serious risks.  

The Center for Pediatric Immunology will change our approach to identifying and treating inborn errors of immunity early in life — and will draw patients from across the country and around the world.

Baby in a patient room at St. Louis Children’s.

Current State

Because genetic errors can take many forms, doctors face tremendous challenges in identifying and addressing the true root causes of a patient’s symptoms. Unfortunately, more than 60% of children with immune system disorders remain undiagnosed. 

With the necessary support for program development, we envision a world where we can accurately diagnose and effectively treat genetically mediated immune disorders as soon as a child is born.

The path forward

Your gifts will allow us to leverage our partnership with the renowned Washington University School of Medicine, not only combining our strengths but connecting our pipelines and resources with the singular purpose of advancing  patients with immune-based diseases from diagnosis to therapy.

The Center of Pediatric Immunology will have a profound impact on our patients, families, clinicians and partners. Together, we will change the way inborn errors of immunity are identified and treated — improving outcomes for children and families around the world.

 

CENTER FOR PEDIATRIC IMMUNOLOGY 
Endow Director, Associate Director and Clinician Positions$7.5 million
Support for Scientific Infrastructure$7.2 million
Support for Seed Fund$3.1 million
TOTAL$17.8 million
Lilly, St. Louis Children’s Hospital Patient

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