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Diphenhydramine (Benadryl) Dosage Table

Diphenhydramine (Benadryl, etc. Dosage Table


Diphenhydramine (Benadryl, etc.) Dosage Table
Child's weight (pounds) 20-24 25-37 38-49 50-99 100+ lbs.
Liquid 12.5mg/5ml (tsp) ¾ 1 2 -- tsp
Chewable 12.5 mg -- 1 2 4 tablets
Tablets 25 mg -- ½ ½ 1 2 tablets
Capsules 25 mg -- -- -- 1 2 caps

Indications: Treatment of allergic reactions, nasal allergies, hives and itching.

Table Notes:

  • AGE LIMITS: For allergies, don't use under 1 year of age (Reason: it's a sedative). For colds, not recommended at any age (Reason: no proven benefits) and should be avoided if under 4 years old. Avoid multi-ingredient products in children under 6 years of age (Reason: FDA recommendations 10/2008).
  • DOSAGE: Determine by finding child's weight in the top row of the dosage table
  • FREQUENCY: Repeat every 6 hours as needed
  • ADULT DOSAGE: 50 mg
  • CHILDREN’S BENADRYL FASTMELTS: Each fastmelt tablet contains the equivalent of 12.5 mg of Diphenhydramine HCL and dosed the same as chewable tablets
  • MEASURING the DOSAGE: Syringes and droppers are more accurate than teaspoons. If possible, use the syringe or dropper that comes with the medication.  If you use a teaspoon, it should be a measuring spoon. Regular spoons are not reliable. Also, remember that 1 level teaspoon equals 5 ml and that ½ teaspoon equals 2.5 ml.

Author and Senior Reviewer: Barton D. Schmitt, M.D.

Content Set: Pediatric HouseCalls Symptom Checker

Pediatric HouseCalls Symptom Checker

St. Louis Children's Hospital is affiliated with Washington University School of Medicine.

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