Clinical Trials
Enrollment into clinical trials provides an opportunity for patients and families to have access to some of the latest therapies that have been developed specifically for pediatric brain tumors. We offer several therapies from large cooperative group studies to smaller, institutional protocols.
Current Trials Available:
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ACNS0221 |
A Phase II Study of Conformal Radiotherapy in Patients with Low Grade Gliomas |
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ACNS0331 |
A Study Evaluating Limited Target Volume Boost Irradiation and Reduced Dose Craniospinal Radiotherapy 18.00 Gy and Chemotherapy In Children with Newly Diagnosed Standard Risk Medulloblastoma: A Phase III Double Randomized Trial |
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ACNS0332 |
Efficacy of Carboplatin Administered Concomitantly With Radiation and Isotretinoin as a Pro-Apoptotic Agent in Other Than Average Risk Medulloblastoma/PNET Patients |
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ACNS0333 |
ACNS0333 Treatment of Atypical Teratoid/Rhabdoid Tumors of the Central Nervous System with Surgery, Intensive Chemotherapy, and 3-D Conformal Radiation |
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ACNS0334 |
A Phase III Randomized Trial for the Treatment of Newly Diagnosed Supratentorial PNET and High Risk Medulloblastoma in Children < 36 Months Old with Intensive Induction Chemotherapy with Methotrexate Followed by Consolidation with Stem Cell Rescue vs. the Same Therapy Without Methotrexate |
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ACNS0621 |
Cilengitide (EMD 121974) (IND# 59073) in Recurrent or Progressive and Refractory Childhood High-Grade Glioma |
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09-0569 |
Head Start III Dose Intensive Chemotherapy For Children Less Than Ten Years of Age Newly-Diagnosed With Malignant Brain Tumors: A Pilot Study of Two Alternative Intensive Induction Chemotherapy Regimens, Followed By Consolidation With Myeloablative Chemotherapy (Thiotepa and Carboplatin, With or Without Etoposide) and Autologous Stem Cell Rescue |
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08-0773 |
A Phase I Trial of Arsenic Trioxide in the Treatment of Infiltrating Gliomas of Childhood |
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Phase II Trial ADVL0525 |
A Phase II Study of Pemetrexed in Children with Recurrent Malignancies |
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Phase I Trial ADVL0714 |
A Phase I Trial of VEGF Trap (NSC# 724770, IND# 100137) in Children with Refractory Solid Tumors |
