Chemotherapy is the use of medicines to treat cancer. The medicines can cause an inflammation of the lining of the mouth. The mouth is lined with mucous membranes. When these are inflamed, it’s called mouth mucositis. The mucous membranes may be red, swollen, painful, irritated, and have sores. The mucositis can affect any part of the digestive system, from the mouth to the anus. Mouth mucositis can be very painful. It can cause problems with eating, talking, and swallowing. It can also lead to serious infections and other problems.

For more information regarding mucositis services in St. Louis, please call 314.454.5437 or 800.678.5437 or email us.


Chemotherapy kills cells that grow fast, such as cancer. Mucous membrane cells also grow fast, so some types of chemotherapy may harm them.

Risk Factors

Children are more likely to get mouth mucositis than adults. Type, dose, and length of time of chemotherapy treatment are factors. A child may also be at higher risk for mouth mucositis because of: 

  • Poor dental and mouth care
  • Loss of body fluid (dehydration)
  • Being underweight
  • Other long-term (chronic) health problems
  • Smoking, using chewing tobacco, or drinking alcohol


Mouth mucositis may start 5 to 10 days after starting chemotherapy. It may last for weeks. Symptoms can also occur a bit differently in each child. They may include:

  • Red, shiny, swollen mouth, tongue, or gums
  • Bleeding in the mouth
  • Sores in the mouth
  • Pain in the mouth or throat
  • Trouble eating, talking, or swallowing
  • Thickened saliva or mucus in the mouth
  • Dryness
  • Imprints of the teeth remain on the tongue (scalloping)
  • A covering or membrane over the mouth sores (pseudomembrane)

The symptoms of mouth mucositis can be like other health conditions. Make sure your child sees a healthcare provider for a diagnosis.


The healthcare provider will ask about your child's chemotherapy treatment and mouth symptoms. He or she will examine your child’s mouth, gums, and tongue. The healthcare provider may note how severe the problem is with a grading system. The mucositis may be graded from 1 to 4. This can help guide treatment. If needed, your child may be tested for other conditions. Some mouth conditions can have similar symptoms, such as oral candidiasis (thrush) or viral infections.

For more information regarding mucositis services in St. Louis, please call 314.454.5437 or 800.678.5437 or email us.


Mouth mucositis can be treated in many ways. Some treatments are simple and may help with mild symptoms. More severe symptoms may need to be treated with prescription medicines. In some cases, your child may need to spend some time in the hospital. Your child's oncologist will work with you to make your child as comfortable as possible. 

To help ease mild symptoms, try the below:

  • Give your child ice pops or ice water to cool and numb his or her mouth.
  • If your child is old enough, give him or her ice chips, hard candy, throat drops (lozenges), or chewing gum.
  • Don’t let your child eat spicy, hot, or rough foods.
  • An older child can use mouth rinses after eating and at bedtime. Your child's oncologist or nurse can suggest rinses to try.
  • Brush your child’s teeth very gently with a soft toothbrush.
  • Use lip balm to keep your child’s lips moist. Don’t use petroleum jelly.

For more severe symptoms, your child's oncologist may advise:

  • Cleaning sores with solutions that you mix or with other products
  • Using pain relievers that are applied to the mouth or taken by mouth (oral)
  • Time in the hospital if your child has an infection, or can’t eat or drink

If your child has severe pain, he or she may need medicine through an IV.


Possible complications of mouth mucositis include:

  • Loss of fluid (dehydration) 
  • Weight loss
  • Infection in the mouth
  • Infection spreading to the blood, which is very serious


Mouth mucositis can’t be fully prevented.  But there are medicines that may help prevent mucositis from happening. Talk with your child's oncologist about these medicines. You can also help lessen the chance and the severity of the condition by making sure your child:

  • Is up to date on all dental care
  • Has dental problems fixed before starting chemotherapy
  • Has excellent mouth care every day, including brushing with a soft toothbrush and mild toothpaste, rinsing, and very gentle flossing
  • Drinks extra liquids
  • Has healthy protein in his or her diet every day
  • Doesn’t smoke, chew tobacco, or drink alcohol, which can all increase the chance of mouth mucositis

Living with

You can help your child during treatment with the below tips:

  • Use a flashlight to check your child's mouth every day. Look for redness, swelling, irritation, and sores.
  • Make sure your child takes excellent care of his or her mouth. This helps to prevent and lessen the symptoms of mouth mucositis. Make sure your child brushes and rinses after eating and at bedtime. Or make sure you clean your child's mouth.
  • Don’t let your child use any mouthwashes or rinses with alcohol. Ask your child's oncologist or nurse what rinse you should use.
  • If your child is taking medicine for pain, give the medicine before your child eats. This can make it easier for your child to eat. 

When to Call a Healthcare Provider

Call your child's healthcare provider if he or she has the below:

  • Redness or shininess in the mouth that lasts for more than 2 days
  • Bleeding gums
  • A cut or sore in the mouth
  • A fever of 100.4°F (38°C) or higher, or as directed by your child's healthcare provider
  • White patches in the mouth
  • Trouble eating, drinking, or taking medicines because of mouth sores

Key Points

  • Mouth mucositis is inflammation of the lining of the mouth (mucous membranes). 
  • Anti-cancer medicines (chemotherapy) may cause mucositis. 
  • Symptoms of mucositis include redness, swelling, irritation, pain, and sores in the mouth. 
  • A child with mucositis may have trouble eating, drinking, swallowing, and talking.
  • There are things you can do to help prevent mucositis from developing, including daily mouth care.
  • Treatment for mucositis may include rinses, medicines by mouth, and staying away from certain foods and products.

Next Steps

Tips to help you get the most from a visit to your child’s healthcare provider:

  • Know the reason for the visit and what you want to happen.
  • Before your visit, write down questions you want answered.
  • At the visit, write down the name of a new diagnosis, and any new medicines, treatments, or tests. Also write down any new instructions your provider gives you for your child.
  • Know why a new medicine or treatment is prescribed and how it will help your child. Also know what the side effects are.
  • Ask if your child’s condition can be treated in other ways.
  • Know why a test or procedure is recommended and what the results could mean.
  • Know what to expect if your child does not take the medicine or have the test or procedure.
  • If your child has a follow-up appointment, write down the date, time, and purpose for that visit.
  • Know how you can contact your child’s provider after office hours. This is important if your child becomes ill and you have questions or need advice.

For more information regarding mucositis services in St. Louis, please call 314.454.5437 or 800.678.5437 or email us.