Hereditary multiple osteochondromatosis (HMO) also known as hereditary multiple exostoses (HME), is a condition in which people develop multiple benign (non-cancerous) bone tumors called exostoses.

The number of exostoses and the bones on which they are located vary greatly among affected individuals. The exostoses are not present at birth, but approximately 96 percent of affected people develop multiple exostoses by the time they are 12 years old.

Common synonyms for HMO include:

  • Diaphyseal aclasis
  • EXT
  • External chondromatosis syndrome
  • Hereditary multiple exostoses
  • Multiple cartilaginous exostoses
  • Multiple exostoses
  • Multiple exostoses syndrome
  • Multiple osteochondromas
  • Multiple osteochondromatosis

For more information about bone tumors or hereditary multiple osteochondromatosis, call 314.454.5437 or 800.678.5437 or email us.

Symptoms of HMO

All children experience hereditary multiple osteochondromatosis differently. Below are the common symptoms associated with the disease:

  • Bone deformity
  • Limited/restricted joint movement
  • Pre-osteoarthritis
  • Peripheral nerve compression
  • Shortened stature
  • Skeletal growth problems

Diagnosis and Treatment of HMO

A pediatric orthopedic doctor can diagnose HMO based on the child’s symptoms, physical examination, and results from bone scans, x-rays, and DNA testing. The goal of treatment for HMO is to relieve pain, improve movement, restore circulation, or improve physical appearance in the child.

Treatment may consist of pain management, surgery, and monitoring for cancer.

For more information about bone tumors or hereditary multiple osteochondromatosis, call 314.454.5437 or 800.678.5437 or email us.