Reduced intensity conditioning: At the Bone Marrow Transplant Program, we perform a reduced intensity conditioning regimen to prepare your child for a stem cell transplant. This means that your child will receive a lower dose of chemotherapy so there are fewer long-term side effects.

However, we balance chemotherapy doses so your child receives enough to prevent graft rejection (when the recipient’s immune system does not accept the donor cells).

Positive outcomes

We have extensive experience performing both allogeneic and autologous bone marrow transplants. Since 1991, we have performed more than 500 autologous and allogeneic transplants. This experience — plus our ongoing research into safer conditioning regimens — has led to positive patient outcomes.  

Comprehensive team approach

Bone marrow transplantation is an incredibly intensive treatment. Physically stressful and potentially life-threatening, bone marrow transplant requires continuous and often long-term hospitalization. Because of this, we collaborate with a wide variety of specialists:

  • Nurses who have specialized training and experience in bone marrow transplant, critical care, and hematology/oncology.

  • Physical therapists, pharmacists, and nutritionists who participate in all aspects of patient care — from daily rounds to follow-up treatment.

  • Pediatric experts in cardiology, gastroenterology, infectious diseases, nephrology, pulmonology, radiation oncology, and surgery.

  • Your child’s referring physicians, to keep them aware of your child's progress and any special concerns that arise.

Extensive pre-transplant evaluation

Because of the risks of a bone marrow transplant, we work with each family to educate them about all potential side effects and outcomes of the process. As part of the pre-transplant process, your family will:

  • Meet with a team that includes a nurse coordinator, social worker, child life specialist, psychologist, school liaison, and chaplain

  • Have the opportunity — through this team — to address any emotional, spiritual, and financial needs you have

  • Learn about the transplant process, including what to expect, potential complications, infection control issues, and finding a bone marrow matched donor

Patient and family support

If your child has a transplant, your pre-evaluation support team will continue to follow your child throughout his or her hospital stay. They will continue to support your family throughout the challenges that lie ahead.

Healing environment

To ensure continuity of care for our families, our inpatient and outpatient staff work closely together. In fact, our outpatient clinic is next to the transplant unit. Our transplant unit and outpatient clinic feature:

  • A six-bed bone marrow transplant unit

  • Private isolation rooms equipped with a HEPA filtration system and state-of-the-art monitoring equipment

  • The ability to protect against infection, a major complication for patients undergoing bone marrow transplants

  • A lounge area with a bathroom and shower, plus a comfortable place where parents can eat, watch TV, or simply relax outside their child's room without being too far away

  • Two large infusion areas, overlooking the hospital's Olson Family Garden and nearby Forest Park

Cure for sickle cell disease

Bone marrow or stem cell transplants can provide a cure for sickle cell disease and thalassemia. Transplant replaces all the blood cells and immune cells from the person getting a transplant with normal donor cells. This provides a cure because it stops the body’s production of abnormal cells.

Clinical trials

As part of a national group of hospitals in pediatric oncology, we are able to offer the latest technologies and treatment options. Please talk to your care team if you are interested in learning about available trials.