A new algorithm for evaluating patients suspected to have hemophagocytic lymphohistiocytosis (HLH) is available in the SLCH Lab Test Guidebook. This diagnostic approach was developed through collaborative efforts of hematology-oncology, rheumatology, PICU and lab medicine. Based on recent publications, this algorithm details a step-wise process for laboratory assessment and subspecialty consultation for patients with a clinical suspicion of HLH (i.e., patients with fever, splenomegaly, cytopenias and/or hepatitis of undetermined etiology). A new HLH lab order bundle has been added to KiDDOS. This algorithm and order set provide a uniform approach for the rapid diagnosis of HLH, which is critical for expedient initiation of appropriate therapy.

For more information about the new HLH guideline, page the lab director at 314.790.0312, or click here to view it online.