Examples of previous major advances in pediatric epilepsy from Washington University School of Medicine include the following:

  • Pediatric Epilepsy ResearchDiscovery of Positron Emission Tomography (PET), an important part of the pre-surgical evaluation of children and adolescents whose seizures do not respond to medication
  • Development of a less invasive form of surgical removal of the middle portion of the temporal lobe (amygdalohippocampectomy), where seizures often arise in children and adolescents whose seizures do not respond to medication
  • Development and evaluation of new anti-epileptic drugs in children
  • Mechanisms of brain cell damage and death, with hope someday of prevention
  • Techniques for directly recording seizures from the surface of the brain

New studies at the Pediatric Epilepsy Center include the following areas:

  • Refining methods for epilepsy surgery
  • Studies of new anti-epileptic drugs
  • Clinical and basic laboratory studies of the ketogenic diet (How does the ketogenic diet work)
  • Clinical decision making in the care of children with epilepsy
  • Assessment of new diagnostic technologies
  • Outcome studies of various forms of pediatric epilepsy
  • Epidemiology of epilepsy in the U.S.A. and in developing countries
  • Thermal regulation and cooling for treatment of seizures
  • Brain-computer interface/neuroprosthetics
  • Genetic markers for adverse effects of drugs